Semi-Recumbent Vibration Therapy in Older Adults

NCT02533063 | Completed Results

• 1 other identifier: 2015-0480
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

This proposed prospective study will evaluate whether a novel exercise approach, seated vibration therapy, can improve function in the target population of older adults. Therefore, the primary aim of this pilot is to examine the effect of vibration therapy on muscle function (balance, muscle power and strength) and muscle mass.

Conditions

Sarcopenia; Aging

Outcome Measures

Primary Outcomes (1)

• Weight Corrected Jump Power Based on Participant's Jump on the Jump Force Plate

  The primary aim of this pilot is to examine the effect of vibration therapy on muscle function. Weight corrected jump power will be the main outcome variable. Countermovement jumps are performed on a Leonardo force plate (Novotec Medical, Pforzheim, Germany) following standard procedures. Jumping mechanography uses maximal countermovement jumps to quantitatively measure muscle strength in the legs. Participants will be asked to perform three countermovement jumps. Participants are asked to try to jump as high as possible using both legs. Three jumps are performed; the jump with the highest jump height is used for analysis.

  This was collected 4 times: Baseline, after 8 week loading/loading+ vibration training, after 4 week washout, after 8 week crossover training.

Secondary Outcomes (6)

• Grip Strength

  Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.

• Gait Speed

  Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.

• Sway

  Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.

• Short Physical Performance Battery (SPPB)

  Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.

• Timed-Up-and-Go (TUG)

  Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.

Other Outcomes (2)

• Adherence and Factors That Influence Adherence-Exercise Enjoyment

  This was collected at the end of each 8 week intervention period.

• Adherence and Factors That Influence Adherence-Pain

  This was collected before and after training during each of the 8 week interventions.

Study Arms (2)

Combination Treatment

ACTIVE COMPARATOR

In the "loading + vibration group" (intervention group), subjects will be seated in the VibeTech One system and vibratory acceleration will be 30Hz and the applied load will be 50% of body weight up to a device maximum applied load of 100 lbs. Vibration intensity will initially be set to 0.2 g and will increase by 0.2 g every other week, as tolerated by the subject, and max out at 1.0 g.

Device: VibeTech One

Sham Treatment

SHAM COMPARATOR

In the "loading only" group (control group) participants will be seated in the vibration device (VibeTech One) and will experience loading of their leg muscles through the device.

Device: VibeTech One

Interventions

VibeTech One DEVICE

Vibration Training The VibeTech One Rehab Chair allows vibration exercise while seated. A force is applied on a footplate that simulates the weight of standing or partial bodyweight. The participants will train for 10 minutes 3 days per week. In the "loading + vibration group" (intervention group) vibratory acceleration will be 30Hz and the applied load will be 50% of body weight up to a device maximum applied load of 100 lbs. Vibration intensity will initially be set to 0.2 g and will increase by 0.2 g every other week, as tolerated by the subject, and max out at 1.0 g.

Combination Treatment; Sham Treatment

Eligibility Criteria

• Age: 70 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Men and women age ≥ 70 years
• Able and willing to sign informed consent
• Able to stand without assistance
• Able and willing to train for 10 minutes, 3 times per week
• Total SPPB score of ≤ 9 or ≤ 2 in any of the three tests included in the SPPB

You may not qualify if:

• Cognitive impairment to the degree that it limits the ability of signing informed consent
• Unable to sit upright for 10 minutes
• History of injury or surgery within the prior six months which limits the ability to ambulate
• Major illness that might cause missed training sessions or visits.

Sponsors & Collaborators

• University of Wisconsin, Madison: lead

Study Sites (1)

Jewish Home and Care Center

Milwaukee, Wisconsin, 53202, United States

Location

Related Publications (1)

• Taani MH, Binkley N, Gangnon R, Krueger D, Buehring B. Effect of semi-recumbent vibration exercise on muscle outcomes in older adults: a pilot randomized controlled clinical trial. BMC Geriatr. 2022 Apr 18;22(1):335. doi: 10.1186/s12877-022-03052-0.

  PMID: 35436920 DERIVED

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Results Point of Contact

• Title: Diane Krueger
• Organization: University of Wisconsin

dckruege@wisc.edu

6082656410

Study Officials

• Bjoern Buehring, M.D.

  University of Wisconsin, Madison

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 19, 2015
• First Posted: August 26, 2015
• Study Start: November 1, 2015
• Primary Completion: February 15, 2017
• Study Completion: February 15, 2017
• Last Updated: April 2, 2019
• Results First Posted: April 2, 2019

Record last verified: 2019-03

Locations

US (1)