Posterior Cornea in Primary Open Angle Glaucoma
1 other identifier
observational
100
1 country
1
Brief Summary
Characterization of posterior corneal changes in primary open angle glaucoma patients, using Scheimpflug examination.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2015
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2015
CompletedFirst Submitted
Initial submission to the registry
February 1, 2015
CompletedFirst Posted
Study publicly available on registry
February 5, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2015
CompletedFebruary 5, 2015
February 1, 2015
3 months
February 1, 2015
February 1, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mean posterior corneal elevation
Mean posterior corneal elevation based on the relative elevation of the cornea related with the best-fit sphere
Single point in time, at baseline at the moment of study enrollment
Secondary Outcomes (1)
Mean anterior corneal elevation
Single point in time, at baseline at the moment of study enrollment
Study Arms (2)
Cases
Patients with primary open angle glaucoma, randomly selected from the Glaucoma Outpatient Clinic to be submitted to Pentacam examination
Controls
Control group of age and central corneal thickness matched healthy subjects, randomly selected from the General Ophthalmology Outpatient Clinic to be submitted to Pentacam examination
Interventions
Eligibility Criteria
Cases from the Glaucoma Outpatient Clinic and controls from the General Ophthalmology Outpatient Clinic from a single ophthalmological center.
You may qualify if:
- Primary open angle glaucoma, with the diagnosis supported on structural and functional complementary exams according to the current European Glaucoma Society guidelines
- Healthy subjects from the General Ophthalmology Outpatient Clinic
You may not qualify if:
- age inferior to 18 years old
- primary closed angle glaucoma
- secondary open angle glaucoma
- previous intra-ocular surgery
- known or suspected corneal disease
- previous intra-ocular inflammation
- previous ocular trauma
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centro Hospitalar Baixo Vouga
Aveiro, Aveiro District, 3814-501, Portugal
Related Publications (1)
Arranz-Marquez E, Bolivar G, Pinero DP, Konstas AG, Mikropoulos DG, Teus MA. Orbscan topography in primary open-angle glaucoma. Optom Vis Sci. 2013 Oct;90(10):1098-103. doi: 10.1097/OPX.0000000000000019.
PMID: 23939294RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Pedro Gil, MSc, MD
Centro Hospitalar Baixo Vouga
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Pedro Gil, MSc, MD
Study Record Dates
First Submitted
February 1, 2015
First Posted
February 5, 2015
Study Start
January 1, 2015
Primary Completion
April 1, 2015
Study Completion
April 1, 2015
Last Updated
February 5, 2015
Record last verified: 2015-02