Anterior Chamber Angle Examination in Angle Closure Suspect Patients

NCT05209204 | Completed

• 1 other identifier: AC angle angle closure suspect
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to detect PACG suspects using both AS OCT and Scheimpflug imaging.

Conditions

Glaucoma

Keywords

Angle closure; ASOCT

Outcome Measures

Primary Outcomes (6)

• Anterior segment parameters as measured by AS-OCT:

  Anterior chamber depth (ACD)..

  3 months

• Anterior segment parameters as measured by Oculus Pentacam:

  Anterior chamber angle (ACA).

  3 months

• Anterior segment parameters by ASOCT

  Angle opening distance at 750 µm (AOD750).

  3 months

• Anterior segment parameters by OCT

  Anterior chamber angle (ACA).

  3 months

• Pentacam parameters

  Anterior chamber volume (ACV).

  3 months

• Pentacam parameters by Oculus Pentacam:

  Anterior chamber depth (ACD).

  3 months

Study Arms (1)

40 pateint glucoma suspect

ASOCT

Diagnostic Test: ASOCT; Diagnostic Test: Pentacam

Interventions

ASOCT DIAGNOSTIC_TEST

Anterior segment imaging using RTVue XR 100 Avanti OCT platform (Optovue Inc.,Fairmont, CA).

40 pateint glucoma suspect

Pentacam DIAGNOSTIC_TEST

Anterior segment imaging using Oculus Pentacam HR (Oculus Optikgeräte, Wetzlar, Germany).

40 pateint glucoma suspect

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Residents of Minia Governorate diagnosed with SLE with renal affection and without renal affection.

You may qualify if:

• Hyperopes. 2-Shallow AC. 3-With gonioscopy carried out under dim-light conditions without indentation ,with the eye in primary position there is inability to visualize ≤ 180° of the posterior trabecular meshwork (TM) in the absence of peripheral anterior 4-IOP ≤ 21 as measured by tonometry. 5-Normal visual field on static automated perimetry (SAP) testing. 5-Normal optic nerve head (ONH) appearance on fundus biomicroscopy. 6-Family history of primary angle closure disease.

You may not qualify if:

• Eyes with significant corneal opacity that can impare signal strings of any of the used imaging modalities.
• Eyes wih history of intraocular surgery (e.g. cataract surgery ,retinal detachment surgery).
• Eyes with history of laser procedures (e.g.laser peripheral iridotomy). 4-Eyes with anterior segment pathology as iridocyclitis or angle disgenesis 5. Eyes with history of trauma. 6- Eyes with findings suggestive of 2dry cause of glaucoma (e.g. iris or angle neovascularization, any iris or corneal abnormalities, dilated episcleral vessels ).

Sponsors & Collaborators

• Minia University: lead

Study Sites (1)

Minia University hospital

Minya, Egypt

Location

MeSH Terms

Conditions

Glaucoma

Condition Hierarchy (Ancestors)

Ocular Hypertension; Eye Diseases

Study Officials

• Mohamed Salah

  Minia University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: January 7, 2022
• First Posted: January 26, 2022
• Study Start: April 1, 2019
• Primary Completion: December 1, 2019
• Study Completion: January 1, 2020
• Last Updated: January 26, 2022

Record last verified: 2022-01

Locations

EG (1)