The Effectiveness of the Meta-cognitive Training Among Patients With Chronic Schizophrenia

NCT02187692 | Completed

• 1 other identifier: MCTPOLAND
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to compare the effectiveness of the meta-cognitive training (MCT) for schizophrenia against treatment as usual (TAU) among patients who attends community support groups. 4 weeks of MCT will be administered for patients two times per week. MCT consists of well structured cognitive behavioral therapy interventions. MCT will be administered according authors recommendations. All participants will be assessed at baseline (T0) and up to one week after the MCT intervention (T1, 4-5 week of the study).

Conditions

Schizophrenia

Keywords

schizophrenia;; meta-cognition;; general functioning;; positive symptoms;; insight;

Outcome Measures

Primary Outcomes (2)

• Psychotic Symptom Rating Scale (The PSYRATS)

  The severity of delusions and hallucinations were assessed at the baseline and after the intervention with the semi-structured Psychotic Symptom Rating Scale. The PSYRATS comprises hallucination and delusions subscale, each design to assess psychological aspects of the symptoms on a five point scale from 0 to 4.

  week 0

• [change] Psychotic Symptom Rating Scale (The PSYRATS)

  The severity of delusions and hallucinations were assessed at the baseline and after the intervention with the semi-structured Psychotic Symptom Rating Scale. The PSYRATS comprises hallucination and delusions subscale, each design to assess psychological aspects of the symptoms on a five point scale from 0 to 4.

  week 4-5

Secondary Outcomes (2)

• Cognitive Biases Questionnairre for Psychosis (CBQp)

  week 0

• [Change] Cognitive Biases Questionnairre for Psychosis (CBQp)

  week 4-5

Other Outcomes (2)

• Neurocognition

  week 0

• [Change] Neurocognition

  week 4-5

Study Arms (2)

TAU

NO INTERVENTION

Treatment as Usual (TAU) vs meta-cogntive training (MCT) condition will be contrasted. In the TAU patients attend regular day programm that includes psychoeducation, social training, vocational rehabilitation, psychotherapy. The MCT condition is an active condition that includes structuralized therapy modules twice a week for four weeks (eight modules in total). There will be no additional differences in the interventions between two groups. Participants will be randomized from patients from the same population into two conditions.

MCT

EXPERIMENTAL

Treatment as Usual (TAU) vs meta-cogntive training (MCT) condition will be contrasted. In the TAU patients attend regular day programm that includes psychoeducation, social training, vocational rehabilitation, psychotherapy. The MCT condition is an active condition that includes structuralized therapy modules twice a week for four weeks (eight modules in total). There will be no additional differences in the interventions between two groups. Participants will be randomized from patients from the same population into two conditions.

Behavioral: MCT

Interventions

MCT BEHAVIORAL

The meta-cognitive training (the MCT) consists of eight structurized psychological therapy modules that provides basic knowledge about cognitive biases that are associated with schizophrenia and it provides the sklills how to overcome negative consequences of the biases. The MCT includes: Module 1 manages self-serving bias (i.e. external-personal attribution for failure, internal attribution for positive events); Module 2 and 7 target the jumping to conclusion; Module 3 and 7 concern beliefs flexibility and bias against disconfirmatory evidence; Module 4 and 6 target deficits in theory of mind; Module 5 is devote to ameliorate the cognitive over-confidence in false memories; Module 8 deals with depressive thinking style.

MCT

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• schizophrenia diagnosis accotding to the ICD-10 criteria
• attending local community support groups for psychitatric patients

You may not qualify if:

• neurological diseases
• substance abuse
• severe psychotic symptoms

Sponsors & Collaborators

• Medical University of Warsaw: lead

Study Sites (1)

II Department of Psychiatry, Medical University of Warsaw

Warsaw, 02-243, Poland

Location

Related Publications (1)

• Gaweda L, Krezolek M, Olbrys J, Turska A, Kokoszka A. Decreasing self-reported cognitive biases and increasing clinical insight through meta-cognitive training in patients with chronic schizophrenia. J Behav Ther Exp Psychiatry. 2015 Sep;48:98-104. doi: 10.1016/j.jbtep.2015.02.002. Epub 2015 Mar 5.

  PMID: 25775947 DERIVED

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Officials

• Łukasz Gawęda, PhD

  II Department of Psychiatry, Medical University of Warsaw

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: October 14, 2013
• First Posted: July 11, 2014
• Study Start: August 1, 2012
• Primary Completion: April 1, 2013
• Study Completion: September 1, 2013
• Last Updated: July 11, 2014

Record last verified: 2013-10

Locations

PL (1)