Bioavailability of Anthocyanins of Blue Potatoes as Compared With Bilberries
1 other identifier
interventional
14
1 country
1
Brief Summary
In this study, the postprandial glycemia and insulinemia caused by boiled potato with blue-fleshed or yellow-fleshed tubers, or a gel prepared with bilberries and potato starch, is studied in healthy males. Additionally, the appearance and metabolism of the flavonoids and their metabolites is studied in plasma and urine.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Dec 2013
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2013
CompletedFirst Submitted
Initial submission to the registry
December 3, 2013
CompletedFirst Posted
Study publicly available on registry
December 9, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2015
CompletedMay 20, 2015
May 1, 2015
1.4 years
December 3, 2013
May 19, 2015
Conditions
Outcome Measures
Primary Outcomes (2)
Plasma glucose concentration
20min, 40min, 60min, 90min, 120min, 180min, 240min
Plasma insulin concentration
20min, 40min, 60min, 90min, 120min, 180min, 240min
Secondary Outcomes (2)
Concentrations and quality of flavonoid color compounds or their metabolites in plasma and urine (HPLC-measurement)
20min, 40min, 60min, 90min, 120min, 180min, 240min
Concentrations and quality of flavonoid color compounds or their metabolites in plasma and urine (NMR-measurement)
20min, 40min, 60min, 90min, 120min, 180min, 240min
Study Arms (3)
Blue-fleshed potato tubers
EXPERIMENTALIntervention: Steam cooked mashed potato tubers
Yellow-fleshed potato tubers
EXPERIMENTALIntervention: Steam cooked mashed potato tubers
Bilberries and potato starch
EXPERIMENTALIntervention: A gel boiled with bilberries and potato starch
Interventions
Eligibility Criteria
You may qualify if:
- Age 18-45
- Male
- No regular medication
- No participation in a drug trial or blood donation within 2 months
- Non-smoker
- Signs informed consent
- Body mass index 18.5-27 kg/m2
- Fasting plasma cholesterol \< 5.5 mmol/l
- Fasting plasma triacylglycerols \< 2.6 mmol/l
- Fasting plasma glucose 4-6 mmol/l
- blood pressure \<140/80 mmHg
- hemoglobin\>130 g/l
- Fasting plasma alanine amino transferase (ALAT) \<60 U/l (normal liver function)
- Fasting plasma thyroid-stimulating hormone (TSH) 0.4 - 4.5 mU/l (normal thyroid function)
- Fasting plasma creatinine \<118 µmol/l (normal kidney function)
You may not qualify if:
- Regular smoking
- Alcohol abuse
- Regular medication
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Biochemistry, University of Turku
University of Turku, Turku, 20014, Finland
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- INVESTIGATOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD
Study Record Dates
First Submitted
December 3, 2013
First Posted
December 9, 2013
Study Start
December 1, 2013
Primary Completion
May 1, 2015
Study Completion
May 1, 2015
Last Updated
May 20, 2015
Record last verified: 2015-05