Study Stopped
Lack of funding
Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.
1 other identifier
interventional
12
1 country
1
Brief Summary
Postprandial glycaemic control is an important risk factor for the development of type 2 diabetes, cardiovascular disease and all-cause mortality. Previous research has demonstrated that exercise performed in the postprandial state paradoxically results in a deterioration in glucose tolerance in the immediate post-exercise period (Gonzalez et a. 2013; Gonzalez and Stevenson 2013). This study aims to assess the timecourse of this post-exercise effect.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Nov 2016
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 13, 2013
CompletedFirst Posted
Study publicly available on registry
November 19, 2013
CompletedStudy Start
First participant enrolled
November 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2017
CompletedAugust 29, 2014
August 1, 2014
3 months
November 13, 2013
August 28, 2014
Conditions
Outcome Measures
Primary Outcomes (1)
Postprandial glucose concentration area under the curve
Blood glucose concentrations will be sampled every 15 min following an oral glucose tolerance test.
90 min
Secondary Outcomes (1)
Postprandial insulin concentration area under the curve
90 min
Study Arms (3)
Rest
ACTIVE COMPARATORBreakfast followed by a rest period prior to OGTT.
Exercise-immediate
EXPERIMENTALBreakfast followed by exercise and an immediate OGTT
Exercise-delay
EXPERIMENTALBreakfast followed by exercise and a delayed (1 h) OGTT.
Interventions
Eligibility Criteria
You may qualify if:
- Normal weight (18-25 kg/m2)
- Physically active (\>or= 3 times per week)
- Male
You may not qualify if:
- Contraindications to exercise
- Food intolerances
- Food allergies
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Northumbria University
Newcastle upon Tyne, Tyne and Wear, NE1 8ST, United Kingdom
Related Publications (2)
Gonzalez JT, Stevenson EJ. Assessment of the post-exercise glycemic response to food: considering prior nutritional status. Nutrition. 2014 Jan;30(1):122-3. doi: 10.1016/j.nut.2013.05.015. Epub 2013 Sep 18. No abstract available.
PMID: 24054351BACKGROUNDGonzalez JT, Veasey RC, Rumbold PL, Stevenson EJ. Breakfast and exercise contingently affect postprandial metabolism and energy balance in physically active males. Br J Nutr. 2013 Aug;110(4):721-32. doi: 10.1017/S0007114512005582. Epub 2013 Jan 29.
PMID: 23340006BACKGROUND
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Javier T Gonzalez, PhD
Northumbria University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Research Fellow
Study Record Dates
First Submitted
November 13, 2013
First Posted
November 19, 2013
Study Start
November 1, 2016
Primary Completion
February 1, 2017
Study Completion
April 1, 2017
Last Updated
August 29, 2014
Record last verified: 2014-08