Whey Protein Intake With and Without Exercise on Visceral Fat: The P+RISE Study

NCT01960335 | Completed

• 1 other identifier: whey-1001-192
• Study Type: interventional
• Target: 79
• Locations: 1 country
• Sites: 1

Brief Summary

Dietary manipulation is proving to be an effective lifestyle strategy to combat the obesity epidemic. Increased dietary protein is one effective strategy. For example, increased whey protein ingestion with and without exercise training is associated with enhanced weight loss, body composition and subjective hunger in overweight and obese individuals. Our findings suggest that the effects of whey protein ingestion occur independent of a calorie-restricted diet and to a greater extent in individuals following a combined exercise program of resistance exercise, sprint intervals, stretching/yoga/pilates, and aerobic exercise training compared to standard resistance training.

Conditions

Obesity; Overweight

Keywords

whey protein intake; obesity; visceral fat; resistance exercise training; sprint interval training; endurance exercise training; yoga training; healthy eating; healthy lifestyle strategies; leptin; hunger

Outcome Measures

Primary Outcomes (1)

• change in visceral fat

  baseline and 17 weeks

Study Arms (3)

Whey Protein Only

ACTIVE COMPARATOR

Ingestion of whey protein only (20 grams per serving) consumed 3X/day along with ad libitum diet for a total of 60 grams per day. One serving was consumed within 1 hour of waking in the morning; a second serving was consumed mid-afternoon; and a third serving was consumed within 2 hours of going to sleep at night.

Dietary Supplement: Whey Protein

Whey Protein and Resistance Exericse

EXPERIMENTAL

Ingestion of whey protein (20 grams per serving) 3X/day: one serving within an hour of waking in morning; a second serving mid-afternoon or within 1 hour immediately following a resistance exercise bout on exercise days; and a third serving within 2 hours of going to bed at night.

Dietary Supplement: Whey Protein; Dietary Supplement: Whey Protein and Resistance Exericse

Whey Protein and RISE exercise routine

EXPERIMENTAL

Ingestion of whey protein (20 gram serving) 3X/day: one serving within an hour of waking in the morning; a second serving mid-afternoon or within 1 hour immediately following the RISE exercise bout; and a third serving within 2 hours of going to bed at night.

Dietary Supplement: Whey Protein; Other: Whey Protein and RISE exercise routine

Interventions

Whey Protein DIETARY_SUPPLEMENT

Whey protein provided in 20 gram servings administered three times per day. once in the morning upon waking; a second serving in the mid-afternoon; and a third serving within 2 hours of going to sleep at night.

Whey Protein Only; Whey Protein and RISE exercise routine; Whey Protein and Resistance Exericse

Whey Protein and Resistance Exericse DIETARY_SUPPLEMENT

Subjects will receive 20 grams of whey protein three times per day along with 4 days per week of resistance exercise training throughout the 16 week intervention.

Whey Protein and Resistance Exericse

Whey Protein and RISE exercise routine OTHER

Subjects will consume 20 grams of whey protein three times per day (total of 60 grams) and perform a combination of exercise involving functional resistance exercise (R); sprint intervals (I); stretching/pilates/yoga (S); and endurance exercise (E); RISE four days per week.

Whey Protein and RISE exercise routine

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• healthy, overweight or obese, inactive

You may not qualify if:

• smoker, exercise-trained, recent weight loss, heavy caffeine-consumer

Sponsors & Collaborators

• Skidmore College: lead

Study Sites (1)

Health & Exercise Sciences Department, Human Nutrition and Metabolism Laboratory, Skidmore College

Saratoga Springs, New York, 12866, United States

Location

Related Publications (1)

• Baer DJ, Stote KS, Paul DR, Harris GK, Rumpler WV, Clevidence BA. Whey protein but not soy protein supplementation alters body weight and composition in free-living overweight and obese adults. J Nutr. 2011 Aug;141(8):1489-94. doi: 10.3945/jn.111.139840. Epub 2011 Jun 15.

  PMID: 21677076 BACKGROUND

MeSH Terms

Conditions

Obesity; Overweight

Interventions

Whey Proteins

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Milk Proteins; Animal Proteins, Dietary; Dietary Proteins; Proteins; Amino Acids, Peptides, and Proteins; Whey; Milk; Dairy Products; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Paul J Arciero, Doctorate

  Skidmore College

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor, Health and Exercise Sciences Department, Director Human Nutrition and Metabolism Laboratory

Study Record Dates

• First Submitted: October 5, 2013
• First Posted: October 10, 2013
• Study Start: January 1, 2011
• Primary Completion: January 1, 2012
• Study Completion: September 1, 2012
• Last Updated: October 10, 2013

Record last verified: 2013-10

Locations

US (1)