NCT01119976

Brief Summary

This is a research study to look at the association between weight loss and the menstrual cycle in healthy, overweight, premenopausal women. Participants will be asked to follow a reduced-calorie diet and exercise plan for 3 months.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2010

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

January 7, 2010

Completed
4 months until next milestone

First Posted

Study publicly available on registry

May 10, 2010

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2010

Completed
Last Updated

December 7, 2012

Status Verified

December 1, 2012

Enrollment Period

7 months

First QC Date

January 7, 2010

Last Update Submit

December 6, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Body weight

    3 months

Secondary Outcomes (1)

  • Waist Circumference

    3 months

Study Arms (2)

Group A

EXPERIMENTAL

Reduced calorie diet and exercise plan that changes with phases of the menstrual cycle

Behavioral: Reduced calorie diet and exercise plan

Group B

ACTIVE COMPARATOR

Different reduced calorie diet and exercise plan based on MyPyramid.gov website

Behavioral: Different reduced calorie diet and exercise plan

Interventions

Participants will receive written diet and exercise instructions to follow for the duration of the study.

Group A

Participants will receive written diet and exercise instructions to follow for the duration of the study.

Group B

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy females between the ages of 18-40 (inclusive)
  • BMI between 26.5-35.4 kg/m² (inclusive)
  • Regular menstrual cycle (28 ± 3 days)
  • Must use barrier contraception (e.g. male/female condom) for the study's duration
  • Must be willing to follow the prescribed diet/exercise plan for the study's duration

You may not qualify if:

  • Any significant health problem (history of cancer, HIV/AIDS, Diabetes, cardiovascular disease, untreated hypothyroidism, etc.)
  • Restrictions against participating in cardiovascular exercise and strength training
  • Women who are pregnant, lactating, or planning to become pregnant during the study period

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Center for Human Nutrition

Denver, Colorado, 80220, United States

Location

MeSH Terms

Conditions

OverweightObesity

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • James O Hill, Ph.D.

    University of Colorado Denver and Health Sciences Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 7, 2010

First Posted

May 10, 2010

Study Start

January 1, 2010

Primary Completion

August 1, 2010

Study Completion

August 1, 2010

Last Updated

December 7, 2012

Record last verified: 2012-12

Locations