NCT01954719

Brief Summary

The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2012

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2012

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

September 19, 2013

Completed
18 days until next milestone

First Posted

Study publicly available on registry

October 7, 2013

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2014

Completed
Last Updated

October 7, 2013

Status Verified

September 1, 2013

Enrollment Period

1.1 years

First QC Date

September 19, 2013

Last Update Submit

October 4, 2013

Conditions

Keywords

Cervix Uteri, Cesarean Section, Infection, Dilatation

Outcome Measures

Primary Outcomes (1)

  • The primary outcome was rate of post-partum endometritis

    The post-partum care for both groups was identical, and included vital signs every four hours, discontinuation of the Foley catheter and advancement of diet on the first postoperative day. All patients in both groups were observed daily in order to assess the following variables: any sign of wound infection (erythema, swelling, discharge or tenderness), vaginal discharge, uterine consistency and height and peritoneal reaction for peritonitis. Clinical signs of urinary tract infection were checked, and urinalysis was performed. A complete blood count was assessed 24 h after delivery. The patients were discharged on third postoperative day if there was no infection or complication.

    All patients in both groups were observed daily,blood count was assessed 24 h after delivery and the patients were discharged on third postoperative day if there was no infection or complication

Secondary Outcomes (1)

  • Secondary outcomes that were analysed included wound infection, febrile morbidity and infectious morbidity.

    Febrile morbidity, blood loss and wound infection diagnosed at least 24 h after surgery

Other Outcomes (1)

  • After elective cesarean section routine cervical dilatation is necessary? Change in post-partum maternal morbidities when compared with a similar group of women receiving intravenous antibiotics and no cervical dilatation at caesarean delivery.

    24 h after surgery

Study Arms (2)

cervix dilated after surgery

EXPERIMENTAL

Digital cervical dilatation performed by surgeon

Procedure: cervix dilated after surgeryProcedure: control group

control group

NO INTERVENTION

cervix not dilated after surgery

Interventions

The surgeon inserted his or her double-gloved index digit in the cervical canal to dilate it and removed the outer gloves after digital dilatation of the cervix.

cervix dilated after surgery
control groupPROCEDURE

surgeon not dilated cervix after surgery

cervix dilated after surgery

Eligibility Criteria

Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bakirkoy Dr Sadi Konuk Training and Research Hospital

Istanbul, Bakirkoy, 34140, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Wound InfectionInfectionsDilatation, Pathologic

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Pathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • hüseyin cengiz, md

    Bakırkoy Dr. Sadi Konuk Training and Research Hospital

    STUDY DIRECTOR

Central Study Contacts

hediye dağdeviren, md

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 19, 2013

First Posted

October 7, 2013

Study Start

November 1, 2012

Primary Completion

December 1, 2013

Study Completion

January 1, 2014

Last Updated

October 7, 2013

Record last verified: 2013-09

Locations