Environmental and Acceptance-Based Innovations for Weight Loss Maintenance
ENACT
1 other identifier
interventional
238
1 country
1
Brief Summary
The major goal of this project is to evaluate an innovative approach to obesity involving modification of the home environment. The project also will evaluate if home environment modification is more effective when supplemented with distress tolerance and related skills training.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable obesity
Started Sep 2011
Longer than P75 for not_applicable obesity
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2011
CompletedFirst Submitted
Initial submission to the registry
June 19, 2012
CompletedFirst Posted
Study publicly available on registry
May 21, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2016
CompletedAugust 5, 2016
August 1, 2016
4.7 years
June 19, 2012
August 3, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Change in Body Weight
Baseline, 6 months, 12 months, 18 months, 24 months
Change in Physical Activity
Objectively measured physical activity will be recorded at each time point.
Baseline, 6 months, 12 months, 18 months, 24 months
Change in Nutritional Intake
Measured by 24-hour food recall
Baseline, 12 months, 24 months
Change in Psychosocial Status
Baseline, 6 months, 12 months, 18 months, 24 months
Study Arms (3)
Behavior Therapy (BT)
ACTIVE COMPARATORActive Comparator: Behavior Therapy Behavioral treatment strategies will be utilized to facilitate adherence to the treatment goals in all three treatments. Participants in the BT condition will receive only the BT intervention. Strategies that will be emphasized are listed below: Self monitoring Stimulus control Changing eating behaviors Goal setting Problem solving Social support Cognitive restructuring Relapse prevention
Behavior Therapy + Environment
EXPERIMENTALParticipants will receive standard behavioral therapy with an emphasis on environmental strategies.
Acceptance-based BT + Environment
EXPERIMENTALParticipants will receive acceptance-based behavioral therapy with an emphasis on environmental strategies.
Interventions
Standard behavioral treatment for weight loss and weight loss maintenance.
Standard behavioral therapy with an emphasis on environmental strategies.
Behavioral therapy with acceptance-based and environmental strategies.
Eligibility Criteria
You may qualify if:
- Have a BMI between 27 and 45 kg/m2
- Have the ability to engage in physical activity (i.e., can walk at least 2 blocks without stopping for rest)
- Successfully complete all steps in the enrollment process, including completion of a 7-day food diary and attendance at all pre-randomization clinic visits
You may not qualify if:
- Have a medical condition (e.g., cancer) or psychiatric condition (e.g., psychotic disorder, substance dependence, bulimia nervosa) that may limit their ability to comply with the behavioral recommendations of the program or pose a risk to the participant during weight loss
- Are pregnant or plan to become pregnant in next 2 years
- Report recently beginning a course of or changing the dosage of prescription medications that can cause significant weight loss or weight gain
- Are participating in or plan to participate in another weight loss program in the next 2 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Drexel University
Philadelphia, Pennsylvania, 19102, United States
Related Publications (4)
Chabria R, Hagerman CJ, Crane N, Ehmann M, Knudsen FM, Brown KL, Forman E, Butryn ML. Racial disparities in the efficacy of traditional versus acceptance-based behavioral weight loss. Health Psychol. 2025 Jul 24:10.1037/hea0001537. doi: 10.1037/hea0001537. Online ahead of print.
PMID: 40705619DERIVEDButryn ML, Call CC, Schumacher LM, Kerrigan SG, Forman EM. Time to Peak Weight Loss During Extended Behavioral Treatment. Obesity (Silver Spring). 2018 Apr;26(4):658-664. doi: 10.1002/oby.22127. Epub 2018 Feb 14.
PMID: 29442440DERIVEDButryn ML, Forman EM, Lowe MR, Gorin AA, Zhang F, Schaumberg K. Efficacy of environmental and acceptance-based enhancements to behavioral weight loss treatment: The ENACT trial. Obesity (Silver Spring). 2017 May;25(5):866-872. doi: 10.1002/oby.21813. Epub 2017 Mar 23.
PMID: 28337847DERIVEDButryn ML, Arigo D, Raggio GA, Kaufman AI, Kerrigan SG, Forman EM. Measuring the Ability to Tolerate Activity-Related Discomfort: Initial Validation of the Physical Activity Acceptance Questionnaire (PAAQ). J Phys Act Health. 2015 May;12(5):717-6. doi: 10.1123/jpah.2013-0338. Epub 2014 Aug 7.
PMID: 25106049DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Ph.D.
Study Record Dates
First Submitted
June 19, 2012
First Posted
May 21, 2013
Study Start
September 1, 2011
Primary Completion
May 1, 2016
Study Completion
May 1, 2016
Last Updated
August 5, 2016
Record last verified: 2016-08