Timing of Meals for Weight Loss

NCT02204735 | Completed DMC

• 1 other identifier: UTK_9560 B
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

While eating the majority of energy earlier in the day appears to have a positive effect on weight and cardiometabolic outcomes, it is not clear how eating earlier in the day influences other behaviors that have a circadian rhythm (sleep), other energy balance behaviors important for weight loss (physical activity), and self-reported feelings of appetite control (hunger and fullness). Thus the purpose of this study is to examine the influence of timing of eating on sleep patterns, physical activity, and self-reported feelings of appetite control. It is hypothesized that those who eat the majority of their calories earlier in the day will have greater weight loss than those who eat the majority later in the day.

Conditions

Overweight; Obesity; Weight Loss

Keywords

Meal Time; Weight Loss; Circadian Rhythm

Outcome Measures

Primary Outcomes (1)

• weight

  Weight will be assessed by an electronic scale, and height will be assessed using a stadiometer, using standard procedures, with participants wearing light clothing, without shoes. BMI (kg/m2) will be calculated from these measures.

  0 and 8 weeks

Secondary Outcomes (4)

• physical activity

  0 and 8 weeks

• sleep

  0 and 8 weeks

• diet

  0 and 8 weeks

• feelings of hunger and fullness

  0 and 8 weeks

Study Arms (2)

MORNING

EXPERIMENTAL

Participants will be instructed to consume 50% of their energy intake in their first eating bout, 30% in their second eating bout, and 20% in their third eating bout. For example, a participant prescribed a 1200 kcal/d diet needs to consume 600 kcal in their first eating bout, 360 kcal in their second bout, and 240 kcal in their third bout. Participants will be provided with sample meal plans meeting this prescription.

Behavioral: Eat majority of calories in the morning

EVENING

EXPERIMENTAL

Participants will be instructed to consume 20% of their energy intake in their first eating bout, 30% in their second eating bout, and 50% in their third eating bout. For example, a participant prescribed a 1200 kcal/d diet needs to consume 240 kcal in their first eating bout, 360 kcal in their second bout, and 600 kcal in their third bout. Participants will be provided with sample meal plans meeting this prescription.

Behavioral: Eat the majority of calories in the evening

Interventions

Eat majority of calories in the morning BEHAVIORAL

MORNING

Eat the majority of calories in the evening BEHAVIORAL

EVENING

Eligibility Criteria

• Age: 25 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• body mass index (BMI) between 27 and 45 kg/m2
• normal self-reported daily (weekday and weekend) wake-up time between 5 am and 8 am
• normal, self-reported weekend wake-up time within two hours of their normal, self-reported weekday wake-up time
• regularly (at least five nights/week) get at least six total hours of self-reported sleep

You may not qualify if:

• report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q)
• report being unable to walk for 2 blocks (1/4 mile) without stopping
• are currently participating in a weight loss program and/or taking weight loss medication or lost \> 5% of body weight during the past 6 months
• are diagnosed with type 1 or 2 diabetes
• have had bariatric surgery or are planning to have bariatric surgery within the next 4 months
• intend to move outside of the metropolitan area within the time frame of the investigation
• are pregnant, lactating, \< 6 months post-partum, or plan to become pregnant during the investigation
• are taking mediation to aid in sleep
• are shift workers/alternative shift workers that work outside of 7 am and 7 pm
• have a metal allergy (which would prevent the ability of participant to wear the SenseWear® armband from BodyMedia® used in the proposed study).

Sponsors & Collaborators

• The University of Tennessee, Knoxville: lead

Study Sites (1)

Univeristy of Tennessee--HEAL Lab

Knoxville, Tennessee, 37996, United States

Location

Related Links

• HEAL research information website

MeSH Terms

Conditions

Overweight; Obesity; Weight Loss

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Body Weight Changes

Study Officials

• Hollie Raynor, Ph, RD

  University of Tennessee

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 28, 2014
• First Posted: July 30, 2014
• Study Start: July 1, 2014
• Primary Completion: November 1, 2017
• Study Completion: November 1, 2017
• Last Updated: April 5, 2018

Record last verified: 2018-04

Locations

US (1)