China Action on Spine and Hip Status

NCT01758770 | Completed DMC

• 1 other identifier: jst2012cash
• Study Type: observational
• Target: 3,457
• Locations: 1 country
• Sites: 1

Brief Summary

1. 1.To determine the prevalences of osteoporotic fracture in elderly Chinese population.
2. 2.To determine the prevalences of osteoporosis in elderly Chinese population using QCT BMD measurement.
3. 3.To investigate the difference in the prevalences of osteoporosis between cities and urban-rural area in China.
4. 4.To investigate the association of body composition with osteoporosis
5. 5.To investigate the prevalence of liver steatosis in China
6. 6.To investigate the application of QCT fat measurement

Conditions

Osteoporosis; Liver Steatosis; Metabolic Syndrome; Obesity

Keywords

osteoporosis; osteoarthritis; bone mineral density; computed xray tomography; liver steatosis; obesity

Outcome Measures

Primary Outcomes (3)

• Osteoporotic fractures

  The spine osteoporotic fractures assessed on the lateral spine image of QCT exam

  5 years

• Bone mineral density (BMD) of spine and hip

  BMD measurement at the spine by QCT and hip

  5 years

• liver steatosis

  The liver steatosis assessed by QCT

  5 years

Secondary Outcomes (3)

• Metabolic syndrome

  5 years

• visceral fat measurement by QCT

  5 years

• Osteoarthritis of spine and hip

  5 years

Eligibility Criteria

• Age: 29 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This is a population-based study, the population of this study is the subset of participants of the large-scale population-based study:the prospective urban rural epidemiology (PURE) in China.

You may qualify if:

• Participants of the PURE study in China (PURE China study)
• be willing to and be able to join in the study and signed Informed consent

You may not qualify if:

• Pregnant
• Spine and both hip implants

Sponsors & Collaborators

• Beijing Jishuitan Hospital: lead
• Fu Wai Hospital, Beijing, China: collaborator
• University of California, San Francisco: collaborator
• Beijing Shi Jing Shan hospital,Beijing, China: collaborator
• Tai yuan central hospital,taiyuan, shanxi: collaborator
• Cheng Du Da Yi hospital,Cheng du, Sichuan: collaborator
• Shen Yang 4th hospital,shen yang, liaoning: collaborator
• Second hospital of sichuan university,Cheng du, Sichuan: collaborator
• Chang Zhou Wu Jin Traditional Chinese Medicine hospital: collaborator
• Red cross hospital of Shaanxi: collaborator
• No 1 TCM hospital of Jiangsu: collaborator
• No 2 TCM hospital of Jiangsu: collaborator
• Chengdu Second people's hospital: collaborator
• Affiliate hospital of jiangxi Traditional Chinese Medicine university: collaborator

Study Sites (1)

Beijing ji shui tan hospitla

Beijing, Beijing Municipality, 100035, China

Location

MeSH Terms

Conditions

Osteoporosis; Fatty Liver; Metabolic Syndrome; Obesity; Osteoarthritis

Condition Hierarchy (Ancestors)

Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases; Liver Diseases; Digestive System Diseases; Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Overweight; Overnutrition; Nutrition Disorders; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Arthritis; Joint Diseases; Rheumatic Diseases

Study Officials

• xiaoguang cheng, MD

  Beijing ji shui tan hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: FAMILY BASED
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chairman, department of radiology

Study Record Dates

• First Submitted: December 26, 2012
• First Posted: January 1, 2013
• Study Start: October 1, 2012
• Primary Completion: July 26, 2017
• Study Completion: July 26, 2017
• Last Updated: March 6, 2018

Record last verified: 2018-03

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)