Key Insights

Highlights

Success Rate

94% trial completion (above average)

Treatment Research

20 treatments under study, led by Teriparatide

Published Results

186 trials with published results (16%)

Research Leaders

20 sponsors active, led by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

4.4%

52 terminated out of 1184 trials

Success Rate

93.7%

+7.1% vs benchmark

Late-Stage Pipeline

22%

259 trials in Phase 3/4

Results Transparency

24%

186 of 780 completed with results

Key Signals

186 with results94% success52 terminated

Data Visualizations

Phase Distribution

819Total
Not Applicable (347)
Early Phase 1 (5)
Phase 1 (83)
Phase 1/2 (11)
Phase 2 (107)
Phase 2/3 (7)
Phase 3 (136)
Phase 4 (123)

Trial Status

Completed780
Unknown176
Recruiting69
Terminated52
Active Not Recruiting33
Not Yet Recruiting32

Trial Success Rate

93.7%

Benchmark: 86.6%

Based on 780 completed trials

Clinical Trials (1184)

Showing 20 of 20 trials
NCT07594639Enrolling By InvitationPrimary

GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP)

NCT02719314RecruitingPrimary

Glucocorticoid-induced Osteoporosis in Patients With Chronic Inflammatory Rheumatic Diseases or Psoriasis

NCT07897929Not ApplicableNot Yet Recruiting

Exercise and Fall Prevention for Fracture Reduction

NCT06745544Not ApplicableActive Not Recruiting

Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes

NCT05666310Phase 4Completed

Muscle Impact of Treating Osteoporosis

NCT05845021Not ApplicableRecruitingPrimary

Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty

NCT07301892Completed

Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis

NCT06018467Phase 2Completed

Senolytics to Improve Osteoporosis Therapy

NCT06853132Not ApplicableCompletedPrimary

Baduanjin With Resistance Training Program

NCT01277562Completed

Pilot Study of Secondary Causes of Osteopenia/Osteoporosis in Adults With Breast and Prostate Cancer

NCT01939470CompletedPrimary

Oklahoma Native American Women's Osteoporosis Screening Study

NCT07436000Not ApplicableCompletedPrimary

AI-Generated Audiovisual Education and Osteoporosis Knowledge

NCT06558188Phase 4Recruiting

Combined Anabolic Therapy

NCT02058420Phase 1/2CompletedPrimary

Tocotrienols and Bone Health of Postmenopausal Women

NCT07848490Not Yet RecruitingPrimary

Osteoporosis & Renal Disease: Research in Primary Health Care Services

NCT07847320Not Yet Recruiting

Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series

NCT05067335Phase 3CompletedPrimary

A Study to Test the Efficacy, Safety and Tolerability of Romosozumab Treatment in Postmenopausal Chinese Women With Osteoporosis

NCT05283148Not ApplicableActive Not Recruiting

Sickle Cell Disease (SCD) Bone Pain Study

NCT06118905Phase 4RecruitingPrimary

Preserving Geriatric Muscle With an Osteoporosis Medication

NCT07645794Enrolling By Invitation

Clinical Study on a New Diagnostic Strategy for Osteoporosis and Sarcopenia in Chronic Kidney Disease Patients Based on MRI-FF

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Research Network

Common Treatments

  • Teriparatide58
  • Denosumab50
  • Zoledronic Acid49
  • Alendronate46
  • Risedronate18

Active Sponsors

  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)35
  • Merck Sharp & Dohme LLC34
  • Eli Lilly and Company33
  • Amgen29
  • National Taiwan University Hospital28

Top Investigators

Related Conditions

  • Osteopenia110
  • Sarcopenia43
  • Breast Cancer30
  • Obesity29
  • Bone Loss21

Activity Timeline