NCT01718405

Brief Summary

Studies have shown that an acute bout of aerobic exercise positively effects cognition, mainly executive functioning; however the effect is not observed among all people and it is not clear whether only aerobic exercise can produce this effect or possibly also resistant exercise. The main purpose of our study is to examine whether genetic variation is a moderator of this effect and whether resistant exercise is comparable to aerobic exercise in improving cognition following a single bout of exercise.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 10, 2012

Completed
21 days until next milestone

First Posted

Study publicly available on registry

October 31, 2012

Completed
1 day until next milestone

Study Start

First participant enrolled

November 1, 2012

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2017

Completed
Last Updated

October 31, 2012

Status Verified

October 1, 2012

Enrollment Period

3 years

First QC Date

October 10, 2012

Last Update Submit

October 29, 2012

Conditions

Executive Function

Outcome Measures

Primary Outcomes (1)

  • Cognitive Functioning After Exercise

    Computerized battery of tests evaluating cognitive functioning

    Five minutes

Other Outcomes (1)

  • Genetic Variation Associated with Different Cognitive Functioning

    Two years

Study Arms (1)

Exercise Group

EXPERIMENTAL

Each individual subject will give a blood sample for genetic analysis and undertake an exercise session and a rest session as a control. Cognitive function will be tested before and after each session.

Other: Cognitive function after exercise testGenetic: Blood sample analysis

Interventions

Cognitive function after exercise testOTHER

The individual subjects will participate in 3 sessions of either aerobic exercise, resistance exercise or rest, in a random order. Before and after each session, the subject will take computerized cognitive tests.

Exercise Group
Blood sample analysisGENETIC

In the first evaluation session blood samples will be taken from each subject and will be analysed for genetic polymorphism.

Exercise Group

Eligibility Criteria

Age20 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Physical Education Students
  • Able to sign consent form

You may not qualify if:

  • Competitive athletes
  • Smokers
  • Neurologic or psychologic orders
  • Chronic diseases
  • Head Injuries
  • Hospitalization in the previous 3 months
  • Pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wingate Institute

Netanya, Israel

Location

Central Study Contacts

Sharon Tsuk, PhD

CONTACT

972-522-640642sharontsuk1@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 10, 2012

First Posted

October 31, 2012

Study Start

November 1, 2012

Primary Completion

November 1, 2015

Study Completion

November 1, 2017

Last Updated

October 31, 2012

Record last verified: 2012-10

Locations

IL(1)