NCT01539694

Brief Summary

The objective of this study is to evaluate the product performance of an investigational multifocal low add soft contact lens.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
126

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2012

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2012

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

February 15, 2012

Completed
12 days until next milestone

First Posted

Study publicly available on registry

February 27, 2012

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2012

Completed
8.6 years until next milestone

Results Posted

Study results publicly available

September 30, 2020

Completed
Last Updated

September 30, 2020

Status Verified

September 1, 2020

Enrollment Period

1 month

First QC Date

February 15, 2012

Results QC Date

August 21, 2020

Last Update Submit

September 9, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Visual Acuity

    Visual acuity was assessed by distance high contrast logarithm of the minimum angle of resolution (logMAR).

    At 1 week follow up

Secondary Outcomes (1)

  • Symptoms/Complaints

    At 1 week follow up

Study Arms (2)

LD118033 contact lens

EXPERIMENTAL

Investigational LD118033 multifocal low add soft contact lenses, to be worn on a daily wear basis.

Device: LD118033 contact lens

PureVision multifocal contact lens

ACTIVE COMPARATOR

PureVision multifocal low add soft contact lens, to be worn on a daily wear basis.

Device: PureVision multifocal contact lens

Interventions

Multifocal contact lens worn on a daily wear basis for 1 week

LD118033 contact lens

PureVision multifocal contact lens worn on a daily wear basis for 1 week.

PureVision multifocal contact lens

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have physiologically normal anterior segments.
  • Be adapted wearers of soft contact lenses and wear a lens in each eye.
  • Be presbyopic and require near add correction in each eye.
  • Have no active ocular disease or allergic conjunctivitis.
  • Must not be using any topical ocular medications.

You may not qualify if:

  • Any Grade 2 or greater finding during the slit lamp examination.
  • Any scar or neovascularization within the central 4mm of the cornea.
  • Any "Present" finding during the slit lamp examination that, in the Investigator's judgment, interferes with contact lens wear.
  • Allergic to any component in the study products.
  • Any systemic disease affecting ocular health.
  • Using any systemic or topical medications that will affect ocular physiology or lens performance.
  • An active ocular disease, any corneal infiltrative response or are using any ocular medications.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch & Lomb Incorporated

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Presbyopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Study Director
Organization
Bausch Health

Study Officials

  • Gerard Cairns, PhD, MCOptom

    Bausch & Lomb Incorporated

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
SCREENING
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 15, 2012

First Posted

February 27, 2012

Study Start

January 1, 2012

Primary Completion

February 1, 2012

Study Completion

March 1, 2012

Last Updated

September 30, 2020

Results First Posted

September 30, 2020

Record last verified: 2020-09

Locations