NCT00886119

Brief Summary

The purpose of the trial is to compare the performance of two multifocal contact lens systems/products in established presbyopic subjects.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2009

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2009

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

April 10, 2009

Completed
12 days until next milestone

First Posted

Study publicly available on registry

April 22, 2009

Completed
9 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2009

Completed
1.5 years until next milestone

Results Posted

Study results publicly available

October 29, 2010

Completed
Last Updated

June 29, 2012

Status Verified

January 1, 2012

Enrollment Period

1 month

First QC Date

April 10, 2009

Results QC Date

September 14, 2010

Last Update Submit

June 26, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Corrected Distance Binocular Visual Measurement in Normal Illumination Reported as Binocular Distance Visual Acuity

    Tested while reading charts distant to the subject with both eyes together in normal lighting. This outcome is measured in logMAR units (logarithm of the minimum angle of resolution). A logMAR acuity of 0.0 equates to 20/20 Snellen acuity and is considered normal. Positive logMAR values indicate poorer vision and negative values denote better visual acuity.

    After 1 week of wear

Study Arms (2)

Lotrafilcon B / Omafilcon A

OTHER

Lotrafilcon B, followed by Omafilcon A

Device: Lotrafilcon B multifocal contact lensDevice: Omafilcon A multifocal contact lens

Omafilcon A / Lotrafilcon B

OTHER

Omafilcon A, followed by Lotrafilcon B

Device: Lotrafilcon B multifocal contact lensDevice: Omafilcon A multifocal contact lens

Interventions

Silicone hydrogel, soft, multifocal contact lens for daily wear use

Lotrafilcon B / Omafilcon AOmafilcon A / Lotrafilcon B

Hydrogel, soft, multifocal contact lens for daily wear use

Lotrafilcon B / Omafilcon AOmafilcon A / Lotrafilcon B

Eligibility Criteria

Age35 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be at least 35 years of age.
  • Best-corrected visual acuity of at least 20/40 in each eye.
  • Spectacle add from +1.50D and +2.50D (inclusive).
  • Able to be fit in available study sphere powers (Plano to -4.00D).
  • Currently wearing soft contact lenses at least 5 days a week.

You may not qualify if:

  • Requires concurrent ocular medication.
  • Eye injury or surgery within twelve weeks immediately prior to enrollment.
  • Currently enrolled in an ophthalmic clinical trial.
  • Evidence of systemic or ocular abnormality, infection or disease likely to affect successful wear of contact lenses or use of their accessory solutions.
  • Previous refractive surgery.
  • Astigmatism \> 1.00D.
  • Currently wearing Proclear Multifocal, Frequency 55 Multifocal or Biomedics EP contact lenses.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Presbyopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Priya Janakiraman, OD, FAAO / Head, Global Clinical Affairs
Organization
CIBA VISION

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 10, 2009

First Posted

April 22, 2009

Study Start

April 1, 2009

Primary Completion

May 1, 2009

Study Completion

May 1, 2009

Last Updated

June 29, 2012

Results First Posted

October 29, 2010

Record last verified: 2012-01