NCT01453465

Brief Summary

This research trial studies biomarkers in samples from patients with rhabdoid tumor of the kidney and atypical teratoid rhabdoid tumor. Studying biomarkers of tissue samples from patients with cancer in the laboratory may help doctors learn more about changes the occur in DNA and identify biomarkers related to cancer.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 1, 2011

Completed
16 days until next milestone

First Posted

Study publicly available on registry

October 17, 2011

Completed
15 days until next milestone

Study Start

First participant enrolled

November 1, 2011

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
Last Updated

August 7, 2018

Status Verified

October 1, 2017

Enrollment Period

1 month

First QC Date

October 1, 2011

Last Update Submit

August 3, 2018

Conditions

Childhood Atypical Teratoid/Rhabdoid TumorRhabdoid Tumor of the Kidney

Outcome Measures

Primary Outcomes (1)

  • Molecular differences between RTK and the ATRT

    Up to 3 months

Study Arms (1)

Ancillary-Correlative (gene expression profile, miRNA profile)

Archived tumor tissue samples are analyzed for gene expression profile and microRNA profile.

Other: Laboratory Biomarker Analysis

Interventions

Laboratory Biomarker AnalysisOTHER

Correlative studies

Ancillary-Correlative (gene expression profile, miRNA profile)

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample

You may qualify if:

  • Samples of RTK and ATRT provided by the Children?s Oncology Group (COG)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Childrens Oncology Group

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

Rhabdoid Tumor

Condition Hierarchy (Ancestors)

Neoplasms, Complex and MixedNeoplasms by Histologic TypeNeoplasms

Study Officials

  • Simone Sredni

    Children's Oncology Group

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 1, 2011

First Posted

October 17, 2011

Study Start

November 1, 2011

Primary Completion

December 1, 2011

Last Updated

August 7, 2018

Record last verified: 2017-10

Locations

US(1)