Success Metrics

Clinical Success Rate
79.5%

Based on 1,971 completed trials

Completion Rate
80%(1971/2479)
Active Trials
346(11%)
Results Posted
64%(1257 trials)
Terminated
508(16%)

Phase Distribution

Ph phase_3
148
5%
Ph phase_4
3
0%
Ph early_phase_1
58
2%
Ph not_applicable
252
8%
Ph phase_1
994
32%
Ph phase_2
1,205
38%

Phase Distribution

1052

Early Stage

1205

Mid Stage

151

Late Stage

Phase Distribution2660 total trials
Early Phase 1First-in-human
58(2.2%)
Phase 1Safety & dosage
994(37.4%)
Phase 2Efficacy & side effects
1,205(45.3%)
Phase 3Large-scale testing
148(5.6%)
Phase 4Post-market surveillance
3(0.1%)
N/ANon-phased studies
252(9.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.3%

1971 of 2653 finished

Non-Completion Rate

25.7%

682 ended early

Currently Active

346

trials recruiting

Total Trials

3,142

all time

Status Distribution
Active(350)
Completed(1971)
Terminated(682)
Other(139)

Detailed Status

Completed1971
Terminated508
Active, not recruiting299
Withdrawn174
unknown127
Recruiting47

Development Timeline

Analytics

Development Status

Total Trials
3142
Active
346
Success Rate
79.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 158 (2.2%)
Phase 1994 (37.4%)
Phase 21205 (45.3%)
Phase 3148 (5.6%)
Phase 43 (0.1%)
N/A252 (9.5%)

Trials by Status

enrolling_by_invitation20%
recruiting471%
active_not_recruiting29910%
not_yet_recruiting20%
suspended120%
unknown1274%
withdrawn1746%
completed197163%
terminated50816%

Recent Activity

Clinical Trials (3,142)

Showing 20 of 3,142 trialsScroll for more
NCT03440567Phase 1

Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma

Completed
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT03180268Phase 3

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Active Not Recruiting
NCT02595424Phase 2

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

Active Not Recruiting
NCT01708954Phase 2

Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Active Not Recruiting
NCT00843882Phase 3

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Active Not Recruiting
NCT00569127Phase 3

Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor

Active Not Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT02567435Phase 3

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Active Not Recruiting
NCT03516617Phase 2

Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Recruiting
NCT02446600Phase 3

Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Active Not Recruiting
NCT00602641Phase 3

Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT01886872Phase 3

Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT00588770Phase 3

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Active Not Recruiting
NCT01856192Phase 2

Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma

Active Not Recruiting
NCT01272037Phase 3

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Active Not Recruiting
NCT02996825Phase 1

Mirvetuximab Soravtansine and Gemcitabine Hydrochloride in Treating Patients With FRalpha-Positive Recurrent Ovarian, Primary Peritoneal, Fallopian Tube, Endometrial, or Triple Negative Breast Cancer

Completed
NCT02432950Not Applicable

Pancreatic Nutritional Program for Weight Loss in Overweight/Obese Patients With Stage I-III Breast Cancer

Completed
NCT00730613Phase 1

Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma

Completed
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting

Drug Details

Intervention Type
OTHER
Total Trials
3,142