Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

18.2%

2 terminated out of 11 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

9%

1 trials in Phase 3/4

Results Transparency

13%

1 of 8 completed with results

Key Signals

1 with results80% success

Data Visualizations

Phase Distribution

9Total
P 1 (7)
P 2 (1)
P 3 (1)

Trial Status

Completed8
Terminated2
Withdrawn1

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (11)

Showing 11 of 11 trials
NCT00653068Phase 3CompletedPrimary

Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

NCT02444546Phase 1Completed

Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

NCT02684071Phase 2Terminated

Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

NCT01453465WithdrawnPrimary

Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor

NCT00919750CompletedPrimary

Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

NCT00326664Phase 1CompletedPrimary

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

NCT01088763Phase 1TerminatedPrimary

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

NCT00946335Phase 1CompletedPrimary

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

NCT00217412Phase 1Completed

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

NCT00100880Phase 1CompletedPrimary

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

NCT01076530Phase 1CompletedPrimary

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Showing all 11 trials

Research Network

Activity Timeline