Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

3.2%

15 terminated/withdrawn out of 474 trials

Success Rate

96.1%

+9.6% vs industry average

Late-Stage Pipeline

24%

114 trials in Phase 3/4

Results Transparency

33%

122 of 366 completed trials have results

Key Signals

33 recruiting122 with results11 withdrawn

Enrollment Performance

Analytics

Phase 3
114(39.0%)
Phase 2
93(31.8%)
Phase 1
67(22.9%)
N/A
18(6.2%)
292Total
Phase 3(114)
Phase 2(93)
Phase 1(67)
N/A(18)

Activity Timeline

Global Presence

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Clinical Trials (474)

Showing 20 of 474 trials
NCT04870944Phase 1Recruiting

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Role: lead

NCT06513962Phase 3Recruiting

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

Role: lead

NCT06647953Phase 3Recruiting

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Role: lead

NCT04293562Phase 3Recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Role: lead

NCT05705531Recruiting

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

Role: lead

NCT06401330Phase 3Recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Role: lead

NCT02402244Recruiting

Project: Every Child for Younger Patients With Cancer

Role: lead

NCT04322318Phase 2Recruiting

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Role: lead

NCT05146739Phase 1Active Not Recruiting

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

Role: collaborator

NCT05602194Phase 3Recruiting

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Role: lead

NCT03959085Phase 3Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Role: lead

NCT05382338Phase 3Recruiting

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Role: lead

NCT05711667Phase 3Recruiting

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Role: lead

NCT02176967Phase 3Active Not Recruiting

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Role: lead

NCT05235165Phase 3Recruiting

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Role: lead

NCT04851119Phase 1Recruiting

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Role: lead

NCT04684368Phase 2Recruiting

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Role: lead

NCT02724579Phase 2Active Not Recruiting

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Role: lead

NCT06620302Phase 1Recruiting

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

Role: lead

NCT04994132Phase 3Active Not Recruiting

A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma

Role: lead