Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

3.2%

15 terminated/withdrawn out of 475 trials

Success Rate

96.2%

+9.6% vs industry average

Late-Stage Pipeline

24%

114 trials in Phase 3/4

Results Transparency

33%

123 of 377 completed trials have results

Key Signals

34 recruiting123 with results11 withdrawn

Enrollment Performance

Analytics

Phase 3
114(38.9%)
Phase 2
93(31.7%)
Phase 1
67(22.9%)
N/A
19(6.5%)
293Total
Phase 3(114)
Phase 2(93)
Phase 1(67)
N/A(19)

Activity Timeline

Global Presence

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Clinical Trials (475)

Showing 20 of 475 trials
NCT01503632Phase 3Completed

Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission

Role: lead

NCT05705531Recruiting

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

Role: lead

NCT05457556Phase 3Active Not Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Role: lead

NCT07072585Phase 2Not Yet Recruiting

Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)

Role: lead

NCT02981628Phase 2Active Not Recruiting

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Role: lead

NCT04195399Phase 2Active Not Recruiting

A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery

Role: lead

NCT07466316Phase 3Recruiting

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

Role: lead

NCT04994132Phase 3Active Not Recruiting

A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma

Role: lead

NCT04293562Phase 3Recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Role: lead

NCT06820957Phase 2Active Not Recruiting

Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body

Role: lead

NCT03223753Phase 3Completed

Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer

Role: lead

NCT00379340Phase 3Completed

Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' Tumor

Role: lead

NCT03190915Phase 2Active Not Recruiting

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

Role: collaborator

NCT06513962Phase 3Recruiting

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

Role: lead

NCT03533582Phase 3Active Not Recruiting

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Role: lead

NCT05382338Phase 3Recruiting

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Role: lead

NCT03959085Phase 3Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Role: lead

NCT02724579Phase 2Active Not Recruiting

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Role: lead

NCT07022678Phase 3Recruiting

Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

Role: lead

NCT06368817Phase 2Recruiting

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Role: lead