Bystander Fatigue and CPR Quality Using Continuous Compressions Versus 30:2 Compressions to Ventilation

NCT01397656 | Completed Results

• 1 other identifier: 2011358-01H
• Study Type: interventional
• Target: 63
• Locations: 1 country
• Sites: 1

Brief Summary

STUDY OBJECTIVES The overall goal of this study is to compare bystander fatigue and CPR quality after 5 minutes of continuous chest compressions versus the 2005 30:2 chest compression to ventilation Resuscitation Guidelines, in a population aged 55 or greater. More specifically, the investigators will compare each CPR ratio with regard to:

1. 1.The achieved frequency and depth of chest compressions, and
2. 2.Participant rating of their perceived level of exertion.
3. 3.less frequent and shallower chest compressions over the 5-minute study period; and
4. 4.higher rating of perceived level of exertion when compared to the 2005 30:2 CPR ratio.

Conditions

Cardiac Arrest

Keywords

cardiac arrest; CPR; resuscitation; fatigue; quality

Outcome Measures

Primary Outcomes (1)

• CPR Quality

  Count of compressions at a depth over 2 inches

  5 minutes

Secondary Outcomes (3)

• Heart Rate

  Assessed immediately before and after 5 minutes of CPR

• Blood Pressure

  Assessed immediately before and after 5 minutes of CPR

• Borg Rating of Perceived Exertion Scale

  Assessed immediately before and after 5 minutes of CPR

Study Arms (2)

CPR 30:2

ACTIVE COMPARATOR

30 chest compressions to 2 ventilations followed by cross-over to CPR with Continuous Compressions

Procedure: CPR using 30:2 ratio

CPR with Continuous Compressions

ACTIVE COMPARATOR

Continuous Chest Compressions without ventilation followed by CPR 30:2 (30 chest compressions to 2 ventilations)

Procedure: CPR using continuous compressions

Interventions

CPR using 30:2 ratio PROCEDURE

Participants will begin performing CPR using a ratio of 30 compressions to 2 ventilations. Participants will then cross over to the other intervention and use continuous compressions.

Also known as: cardiopulmonary resuscitation

CPR 30:2

CPR using continuous compressions PROCEDURE

Participants will begin performing CPR using continuous chest compressions. Participants will then cross-over to the other intervention arm and perform CPR using a ratio of 30 compressions to 2 ventilations.

Also known as: cardiopulmonary resuscitation

CPR with Continuous Compressions

Eligibility Criteria

• Age: 55 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male or female person aged 55 or older
• Must score 3 or less on the validated Clinical Frailty Scale
• Able to follow instructions in English or French
• Able to understand and give informed consent

You may not qualify if:

• Musculoskeletal condition precluding the ability to kneel down and perform CPR (e.g. severe arthritis, cast, wrist sprain, recent joint surgery)
• Cardiovascular condition precluding the ability to perform a moderate effort (e.g. myocardial infarction or cardiovascular procedure in the last 3 months, recurrent angina, chest pain under investigation)
• Pulmonary condition precluding the ability to perform a moderate effort (e.g. emphysema, severe asthma, pneumonia)
• Active communicable disease (e.g. tuberculosis, meningitis, gastro enteritis, hepatitis A or B, herpes simplex)
• Inability to perform chest compressions at appropriate rate and depth despite positive feedback during one to two-minute practice session

Sponsors & Collaborators

• Ottawa Hospital Research Institute: lead

Study Sites (1)

The Ottawa Hospital, Civic Campus

Ottawa, Ontario, K1Y4E9, Canada

Location

Related Publications (2)

• Vaillancourt C, Midzic I, Taljaard M, Chisamore B. Performer fatigue and CPR quality comparing 30:2 to 15:2 compression to ventilation ratios in older bystanders: A randomized crossover trial. Resuscitation. 2011 Jan;82(1):51-6. doi: 10.1016/j.resuscitation.2010.09.003. Epub 2010 Oct 14.

  PMID: 20947241 BACKGROUND

• Liu S, Vaillancourt C, Kasaboski A, Taljaard M. Bystander fatigue and CPR quality by older bystanders: a randomized crossover trial comparing continuous chest compressions and 30:2 compressions to ventilations. CJEM. 2016 Nov;18(6):461-468. doi: 10.1017/cem.2016.373. Epub 2016 Sep 21.

  PMID: 27650514 RESULT

MeSH Terms

Conditions

Heart Arrest; Fatigue

Interventions

Cardiopulmonary Resuscitation

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Resuscitation; Emergency Treatment; Therapeutics

Results Point of Contact

• Title: Dr. Christian Vaillancourt
• Organization: Ottawa Hospital Research Institute

cvaillancourt@ohri.ca

613-798-5555

Study Officials

• Christian Vaillancourt, MD, MSc

  Ottawa Hospital Research Institute

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 13, 2011
• First Posted: July 19, 2011
• Study Start: July 1, 2011
• Primary Completion: August 1, 2011
• Study Completion: September 1, 2011
• Last Updated: November 15, 2018
• Results First Posted: November 15, 2018

Record last verified: 2017-06

Locations

CA (1)