OPALS Critical Care Sub-Studies

NCT00212953 | Completed

• 1 other identifier: 1997576-01H
• Study Type: interventional
• Target: 21,000
• Locations: 1 country
• Sites: 11

Brief Summary

The purpose of the study is to evaluate the incremental benefit of a full advanced life support EMS program on the outcomes of chest pain, respiratory and major trauma patients.

Conditions

Cardiac Arrest

Keywords

Chest Pain,; Shortness of breath,; Injury,; Trauma

Outcome Measures

Primary Outcomes (1)

• Survival to discharge

Secondary Outcomes (8)

• Generic Quality of Life

• Disease Specific Quality of Life CPC Score and FIM Score

• Performance of ALS Procedures

• Response Time Intervals

• Length of Stay in Hospital

Interventions

Advanced Life Support PROCEDURE

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Chest Pain Sub-Study: Adult patients with a complaint of chest pain of an acute nature transported to hospital by ambulance. Patients with a complaint of pain in arms, neck or jaw if consistent with myocardial ischemia. Patients must have an ambulance return code of prompt, urgent, or no patient carried.
• Respiratory Sub-Study: Adult patients with a chief complaint of shortness of breath defined as ACR codes of Respiratory Failure, Shortness of Breath NYD, Pulmonary Edema (CHF), Asthma and had either prehospital assisted ventilation or abnormal respiratory rates (\>=24 or \<=10)
• Major Trauma Sub-Study: Adult patients who have suffered an injury from any mechanism with an Injury Severity Score of \>12 who have been transported to hospital by land ambulance, and who have been entered into the Ontario Trauma Registry (OTR) Comprehensive Data Set.

You may not qualify if:

• All Sub-Studies:
• Patients under the age of 16
• Patients who are vital signs absent prior to EMS arrival.
• Chest Pain Sub-Study:
• Patients suffering primarily from respiratory distress, respiratory failure, pulmonary edema, asthma, palpitations or epigastric pain. pain

Sponsors & Collaborators

• Ottawa Hospital Research Institute: lead
• Ontario Ministry of Health and Long Term Care: collaborator

Study Sites (11)

Cambridge Base Hospital

Cambridge, Ontario, N3C 3X4, Canada

Location

Sudbury Base Hospital

Greater Sudbury, Ontario, 705-675-4783, Canada

Location

Kingston Base Hospital

Kingston, Ontario, K7L 1S4, Canada

Location

London Base Hospital

London, Ontario, N6A 4G5, Canada

Location

Halton Base Hospital

Mississauga, Ontario, L6K 3S3, Canada

Location

Niagara Falls Base Hospital

Niagara Falls, Ontario, L2E 6X2, Canada

Location

Ottawa Base Hospital

Ottawa, Ontario, K1H 8L6, Canada

Location

Peterborough Base Hospital

Peterborough, Ontario, K9J 7C6, Canada

Location

Lambton Base Hospital

Sarnia, Ontario, N7T 6S3, Canada

Location

Thunder Bay Base Hospital

Thunder Bay, Ontario, P7E 1G6, Canada

Location

Windsor Base Hospital

Windsor, Ontario, N9A 1E1, Canada

Location

MeSH Terms

Conditions

Heart Arrest; Chest Pain; Dyspnea; Wounds and Injuries

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Respiratory Tract Diseases; Signs and Symptoms, Respiratory

Study Officials

• Ian Stiell, MD

  OHRI

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 13, 2005
• First Posted: September 21, 2005
• Study Start: March 1, 1997
• Study Completion: May 1, 1999
• Last Updated: October 15, 2010

Record last verified: 2010-10

Locations

CA (11)