Molecular Analysis of Thoracic Malignancies

NCT01385722 | Enrolling By Invitation DMC

• 3 other identifiers: IRB-21319SU-06232011-7986THOR0004
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

A research study to learn about the biologic features of cancer development, growth, and spread. We are studying components of blood, tumor tissue, normal tissue, and other fluids, such as urine, cerebrospinal fluid, abdominal or chest fluid in patients with cancer. Our analyses of blood, tissue, and/or fluids may lead to improved diagnosis and treatment of cancer by the identification of markers that predict clinical outcome, markers that predict response to specific therapies, and the identification of targets for new therapies.

Conditions

Thymus Cancer; Thymoma; Thymic Carcinoma; Lung Cancer; Carcinoma, Non-Small-Cell Lung; Mesothelioma

Outcome Measures

Primary Outcomes (1)

• Collect detailed clinical information on patients with thoracic malignancies via the electronic medical record and a detailed patient questionnaire

  20 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be identified who come to the Stanford Cancer Center seeking a Thoracic Oncology medical opinion for their disease.

You may qualify if:

• Histologically proven diagnosis of non-small cell lung cancer, small cell lung cancer, thymoma, thymic carcinoma, mesothelioma, or carcinoma of unknown primary consistent with the presentation of a primary thoracic malignancy.
• years of age or older.
• Ability to understand and the willingness to sign a written informed consent document.

Sponsors & Collaborators

• Stanford University: lead

Study Sites (1)

Stanford University School of Medicine

Stanford, California, 94305, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

The potential tumor tissues to be collected include paraffin-embedded tissue, frozen tissues, or fresh tissue. These will be stored in conjunction with the Stanford Tissue Bank.

MeSH Terms

Conditions

Thymus Neoplasms; Thymoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Mesothelioma

Condition Hierarchy (Ancestors)

Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lymphatic Diseases; Hemic and Lymphatic Diseases; Neoplasms, Complex and Mixed; Neoplasms by Histologic Type; Respiratory Tract Neoplasms; Lung Diseases; Respiratory Tract Diseases; Carcinoma, Bronchogenic; Bronchial Neoplasms; Adenoma; Neoplasms, Glandular and Epithelial; Neoplasms, Mesothelial

Study Officials

• Joel Neal

  Stanford University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 28, 2011
• First Posted: June 30, 2011
• Study Start: August 1, 2011
• Primary Completion (Estimated): June 1, 2031
• Study Completion (Estimated): June 1, 2031
• Last Updated: December 26, 2025

Record last verified: 2025-12

Locations

US (1)