Key Insights

Highlights

Success Rate

65% trial completion

Published Results

11 trials with published results (26%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

16.7%

7 terminated out of 42 trials

Success Rate

65.0%

-21.5% vs benchmark

Late-Stage Pipeline

2%

1 trials in Phase 3/4

Results Transparency

85%

11 of 13 completed with results

Key Signals

11 with results65% success

Data Visualizations

Phase Distribution

37Total
Not Applicable (2)
P 1 (8)
P 2 (26)
P 3 (1)

Trial Status

Completed13
Recruiting8
Terminated7
Active Not Recruiting6
Not Yet Recruiting4
Unknown3

Trial Success Rate

65.0%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (42)

Showing 20 of 20 trials
NCT01025089Phase 2Active Not Recruiting

Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma

NCT03076554Phase 2Active Not Recruiting

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

NCT07693855Not ApplicableNot Yet Recruiting

Hypofractionated Adjuvant Radiotherapy for Thymic Epithelial Tumors

NCT06790706Phase 2Active Not Recruiting

IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the Safety and the Efficacy of the IMMUNOtherapy With Domvanalimab + Zimberelimab Combination in Patients With Advanced RARE Cancers

NCT07598955Phase 1Recruiting

Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic Carcinoma

NCT03134118Phase 2Active Not Recruiting

Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM)

NCT06019468Phase 2RecruitingPrimary

Neoadjuvant Treatment For Locally Advanced Thymic Cancer

NCT07324629Phase 2Not Yet RecruitingPrimary

Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic Carcinoma

NCT06402708Phase 3RecruitingPrimary

Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)

NCT03463460Phase 2Active Not RecruitingPrimary

Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic Cancer

NCT07479628Phase 2Not Yet RecruitingPrimary

Neoadjuvant Adebrelimab Plus CRT for Locally Advanced Thymic Carcinoma

NCT07328074Not Yet Recruiting

Electrocautery Resection Combined With HITHOC for Thymic Epithelial Tumors With Pleural Metastasis

NCT06248515Phase 2Recruiting

A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors

NCT01385722Enrolling By Invitation

Molecular Analysis of Thoracic Malignancies

NCT06838910Phase 2RecruitingPrimary

Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic Carcinoma

NCT07181720Phase 1Recruiting

CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors

NCT07179341Not ApplicableCompletedPrimary

Survival Nomogram for Patients With Thymic Carcinoma

NCT05667948Recruiting

Molecular Analysis and Treatment Options of Thymic Malignancies

NCT03583086Phase 1CompletedPrimary

Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors

NCT03921671Phase 2Active Not RecruitingPrimary

Ramucirumab and Carbo-Paclitaxel for Untreated Thymic Carcinoma / B3 Thymoma With Carcinoma (RELEVENT)

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