Key Insights

Highlights

Success Rate

72% trial completion

Published Results

198 trials with published results (28%)

Research Maturity

321 completed trials (46% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

18.0%

126 terminated out of 699 trials

Success Rate

71.8%

-14.7% vs benchmark

Late-Stage Pipeline

15%

108 trials in Phase 3/4

Results Transparency

62%

198 of 321 completed with results

Key Signals

198 with results72% success126 terminated

Data Visualizations

Phase Distribution

580Total
Not Applicable (41)
Early P 1 (4)
P 1 (179)
P 2 (248)
P 3 (92)
P 4 (16)

Trial Status

Completed321
Terminated126
Unknown98
Recruiting63
Active Not Recruiting55
Withdrawn18

Trial Success Rate

71.8%

Benchmark: 86.6%

Based on 321 completed trials

Clinical Trials (699)

Showing 20 of 20 trials
NCT05872763CompletedPrimary

A Study of Participants in China With Non-Small-Cell Lung Cancer That is Unable to be Treated With Surgery

NCT04603807Phase 3Active Not RecruitingPrimary

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

NCT07154290Phase 2Recruiting

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

NCT05642195Phase 1Suspended

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

NCT07760519Not Yet RecruitingPrimary

A Multicenter Observational PMS Study Assessing Durvalumab Safety in Indian Adults With Resectable NSCLC

NCT06623422Phase 3RecruitingPrimary

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

NCT06515990Phase 1RecruitingPrimary

A Study of DM005 in Patients With Advanced Solid Tumors

NCT06890598Phase 3RecruitingPrimary

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT03706690Phase 3Active Not RecruitingPrimary

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

NCT06862869RecruitingPrimary

Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy

NCT07680907Not Yet RecruitingPrimary

A Real World Study of Participants With Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor Mutation (EGFRm)

NCT07586202Phase 2RecruitingPrimary

A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLC

NCT07230691RecruitingPrimary

A Study of Clinical Outcomes in Participants With EGFR Mutated Advanced Non-Small Cell Lung Cancer (NSCLC) in a Real-World Setting

NCT07227025Phase 1RecruitingPrimary

A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

NCT06532032Phase 1CompletedPrimary

A Study of Combination Therapy With Amivantamab and Docetaxel in Participants With Metastatic Non-small Cell Lung Cancer

NCT06667076Phase 2RecruitingPrimary

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

NCT05488314Phase 1Active Not RecruitingPrimary

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

NCT05663866Phase 2Active Not RecruitingPrimary

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

NCT06120140Phase 2Active Not RecruitingPrimary

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

NCT02905591Phase 2Active Not RecruitingPrimary

A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC

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