Research on Aging Project in Iceland: Second Stage
Age, Gene/Environment Susceptibility (AGES) Study
2 other identifiers
observational
5,764
1 country
1
Brief Summary
Background: \- Researchers are interested in studying the environmental and genetic factors that play a role in health and living conditions as people age. Since 2002, the U.S. National Institute on Aging and the Icelandic Heart Association Research Institute have been conducting a long-term study known as the Research in Aging project to collect personal data and samples from Icelandic men and women in order to study risk factors related to disease and disability in old age. Researchers plan to initiate a second stage of the study. Objectives: \- To collect additional personal information, medical records, and blood samples from individuals who have previously provided materials for the Research in Aging Project in Iceland. Eligibility: \- Individuals who have previously participated in the Research in Aging project in association with the U.S. National Institute on Aging and the Icelandic Heart Association Research Institute. Design:
- Participants will have a physical examination with imaging analysis procedures and hearing and eye tests, provide information on health and diet, and provide a 100-ml blood sample for testing.
- Participants will also provide consent for researchers to consult data and samples collected during the first stage of the Research on Aging project.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2003
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 31, 2003
CompletedFirst Submitted
Initial submission to the registry
March 23, 2011
CompletedFirst Posted
Study publicly available on registry
March 24, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
February 11, 2014
CompletedNovember 12, 2019
February 11, 2014
March 23, 2011
November 8, 2019
Conditions
Keywords
Eligibility Criteria
You may qualify if:
- Individuals who have previously participated in the Research in Aging project in association with the U.S. National Institute on Aging and the Icelandic Heart Association Research Institute.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Icelandic Heart Association Research Institute
Kopavogur, Iceland
Related Publications (4)
Freimer N, Sabatti C. The human phenome project. Nat Genet. 2003 May;34(1):15-21. doi: 10.1038/ng0503-15. No abstract available.
PMID: 12721547BACKGROUNDRoss R. Atherosclerosis--an inflammatory disease. N Engl J Med. 1999 Jan 14;340(2):115-26. doi: 10.1056/NEJM199901143400207. No abstract available.
PMID: 9887164BACKGROUNDErshler WB, Keller ET. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med. 2000;51:245-70. doi: 10.1146/annurev.med.51.1.245.
PMID: 10774463BACKGROUNDSchelbert EB, Cao JJ, Sigurdsson S, Aspelund T, Kellman P, Aletras AH, Dyke CK, Thorgeirsson G, Eiriksdottir G, Launer LJ, Gudnason V, Harris TB, Arai AE. Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults. JAMA. 2012 Sep 5;308(9):890-6. doi: 10.1001/2012.jama.11089.
PMID: 22948699DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Tamara B Harris, M.D.
National Institute on Aging (NIA)
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- NIH
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 23, 2011
First Posted
March 24, 2011
Study Start
January 31, 2003
Study Completion
February 11, 2014
Last Updated
November 12, 2019
Record last verified: 2014-02-11