Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia
2 other identifiers
interventional
100
1 country
1
Brief Summary
The aim of the investigators analysis is to identify the neural correlates of quality of life scores in schizophrenia. For this, the investigators will constitute group of patients according to their quality of life scores and the investigators will analyze their differences in patterns of brain structures and activations.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable schizophrenia
Started Jan 2011
Longer than P75 for not_applicable schizophrenia
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2011
CompletedFirst Submitted
Initial submission to the registry
February 9, 2011
CompletedFirst Posted
Study publicly available on registry
February 14, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2015
CompletedApril 28, 2015
April 1, 2015
4 years
February 9, 2011
April 27, 2015
Conditions
Outcome Measures
Primary Outcomes (1)
to study the relationships between quality of life and the morphologic, structural and functional substrates in schizophrenia
36 months
Secondary Outcomes (1)
to determine whether quality of life is correlated with brain modifications using functional Magnetic Resonance Imaging
36 months
Study Arms (1)
schizophrenia PATIENTS
OTHERInterventions
Eligibility Criteria
You may qualify if:
- diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria (American Psychiatric Association(APA), 1994),
- age over 18 years,
- informed consent to participate in the studies
- French as native language
You may not qualify if:
- diagnosis other than schizophrenia on Axis I of DSM-IV,
- decompensated organic disease and mental retardation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assistance Publique Hopitaux de Marseille
Marseille, 13354, France
Related Publications (1)
Faget-Agius C, Boyer L, Wirsich J, Ranjeva JP, Richieri R, Soulier E, Confort-Gouny S, Auquier P, Guye M, Lancon C. Neural substrate of quality of life in patients with schizophrenia: a magnetisation transfer imaging study. Sci Rep. 2015 Dec 3;5:17650. doi: 10.1038/srep17650.
PMID: 26632639DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
BERNARD BELAIGUES
Assistance Publique hôpitaux de Marseille
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 9, 2011
First Posted
February 14, 2011
Study Start
January 1, 2011
Primary Completion
January 1, 2015
Study Completion
September 1, 2015
Last Updated
April 28, 2015
Record last verified: 2015-04