The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance

NCT01244360 | Unknown

• 2 other identifiers: MU Smoliga Resveratrol2RESMU194218
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to examine the effects of resveratrol on health and human performance. The study will evaluate cognitive function and several indicators of physical health before and after taking a resveratrol supplement or a placebo for three weeks.

Conditions

Inflammation

Keywords

resveratrol; insulin; inflammation; cognition; metabolism

Outcome Measures

Primary Outcomes (1)

• Vascular function

  vascular response to stress will be measured using flow mediated dilation and ultrasound.

  4 weeks, with option of additional 4 week treatment period

Secondary Outcomes (3)

• Body fat percentage

  4 weeks, with optional additional 4 week treatment period

• inflammation biomarkers

  4 weeks, with optional additional 4 week treatment period

• cognitive function

  4 weeks, with optional additional 4 week treatment period

Study Arms (2)

Sugar Pill

PLACEBO COMPARATOR

Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.

Other: Placebo Comparator: Sugar Pill

Dietary Supplement: resveratrol

ACTIVE COMPARATOR

Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.

Dietary Supplement: resveratrol

Interventions

resveratrol DIETARY_SUPPLEMENT

Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.

Dietary Supplement: resveratrol

Placebo Comparator: Sugar Pill OTHER

Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.

Sugar Pill

Eligibility Criteria

• Age: 45 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• men and women between 45 and 75 years of age
• Normal heart rate and Blood pressure
• Ability to use personal computer interface
• Successful completion of physical activity readiness questionnaire

You may not qualify if:

• Cardiovascular disease, uncontrolled hypertension, lung disease
• inability to tolerate exercise
• have taken grape related supplement in past 12 months
• current use of drugs or dietary supplements to enhance exercise performance
• allergy to wine, grape juice or grape seed supplements

Sponsors & Collaborators

• Marywood University: lead

Study Sites (1)

Marywood University

Scranton, Pennsylvania, 18509, United States

Location

MeSH Terms

Conditions

Inflammation; Insulin Resistance

Interventions

Resveratrol

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Stilbestrols; Stilbenes; Benzylidene Compounds; Benzene Derivatives; Hydrocarbons, Aromatic; Hydrocarbons, Cyclic; Hydrocarbons; Organic Chemicals; Polyphenols; Phenols

Study Officials

• James Smoliga, Ph.D.

  Marywood University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: November 17, 2010
• First Posted: November 19, 2010
• Study Start: November 1, 2010
• Primary Completion: June 1, 2011
• Study Completion: June 1, 2011
• Last Updated: June 2, 2011

Record last verified: 2011-06

Locations

US (1)