NCT01235858

Brief Summary

There is an increasing trend in the incidence of infection related to epidural anesthesia. This could be related to methods of aseptic technique as adopted by the anesthesiologist during the performance of the procedure. The purpose of this study is to compare two methods of aseptic technique for labor epidural insertion; a "conventional" method without wearing a sterile gown (free from living germs or microorganisms) versus strict aseptic method with wearing of sterile gowns. It is our belief that there will be an increased contamination of epidural equipment and colonization of epidural catheter, secondary to bacterial fallout from the operators' bare hands in the group not wearing the sterile gowns.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
240

participants targeted

Target at P50-P75 for not_applicable pregnancy

Timeline
Completed

Started Nov 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2009

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

September 27, 2010

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2010

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 8, 2010

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

April 4, 2012

Status Verified

July 1, 2011

Enrollment Period

1 year

First QC Date

September 27, 2010

Last Update Submit

April 3, 2012

Conditions

Keywords

Epidural analgesiaEpidural anesthesia laborAseptic techniquegownno gown

Outcome Measures

Primary Outcomes (1)

  • Growth of microbial organisms on operators forearm, agar plate (working area) and proximal and distal tip of the epidural catheter.

    one and one half year

Secondary Outcomes (1)

  • length of epidural catheterization and positive culture

    one year and a half

Study Arms (2)

Gown group

OTHER

Anesthesiologists wearing sterile gown for epidural insertion

Procedure: wearing of sterile gowns

No Gown group

OTHER

Anesthesiologists not wearing gown for epidural insertion

Procedure: No gown

Interventions

Anesthesiologists wearing sterile gown for epidural insertion

Also known as: Sterile gowns
Gown group
No gownPROCEDURE

Anesthesiologists not wearing sterile gown for epidural insertion

No Gown group

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All pregnant women requesting epidural analgesia

You may not qualify if:

  • Patients who have fever requiring antibiotics
  • Patients who have received antibiotics in or within the previous 48 hours of labor
  • Immuno-compromised patients.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Anesthesia Mount Sinai Hospital

Toronto, Ontario, M5G 1X5, Canada

Location

Related Publications (1)

  • Siddiqui NT, Davies S, McGeer A, Carvalho JC, Friedman Z. The effect of gowning on labor epidural catheter colonization rate: a randomized controlled trial. Reg Anesth Pain Med. 2014 Nov-Dec;39(6):520-4. doi: 10.1097/AAP.0000000000000171.

Study Officials

  • Naveed T Siddiqui, MD

    Department of Anesthesia and Pain Management Mount Sinai Hospital, Toronto,Canada

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

September 27, 2010

First Posted

November 8, 2010

Study Start

November 1, 2009

Primary Completion

November 1, 2010

Study Completion

December 1, 2011

Last Updated

April 4, 2012

Record last verified: 2011-07

Locations