Effects of Physical Activity During Pregnancy on the Newborn's Cognitive Function
1 other identifier
interventional
N/A
1 country
1
Brief Summary
Background: It is now generally accepted that an active lifestyle is beneficial for cognition, but can these benefits be transmitted for the active pregnant woman to her unborn child? This has been demonstrated in rats where the pups born of mothers who exercised during pregnancy had increased hippocampal neurogenesis and better memory and learning capabilities. Human studies tend to confirm this by looking at behavioral results, ie. better orientation and state regulation skills in newborns. The aim of the present study is to verify this on the electrophysiological level and to determine the effects of an active lifestyle during pregnancy on the newborn's brain development. Methods: 60 pregnant women will be included in a randomized controlled trial. The exercise group will be asked to exercise a minimum of 20 minutes, 3 times per week, at a minimal intensity of 55% of their maximal aerobic capacity. The control group will not be given exercise counselling. Newborns' brain activity will be recorded using electroencephalography (EEG) 10 days post partum. The primary outcome measure will be the amplitude and latency of the mismatch negativity (MMN), a component of the auditory event-related potential (ERP) that can be used to investigate the auditory sensory memory.
Trial Health
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 13, 2010
CompletedFirst Posted
Study publicly available on registry
October 14, 2010
CompletedOctober 14, 2010
September 1, 2010
October 13, 2010
October 13, 2010
Conditions
Outcome Measures
Primary Outcomes (1)
Mismatch negativity
Study Arms (2)
Exercise
EXPERIMENTALControl
NO INTERVENTIONInterventions
Eligibility Criteria
You may qualify if:
- First trimester of pregnancy
- to 35 years of age
- Pre-pregnancy BMI between 18 and 25
- Primipara
- Without any known health issues
- Use of folic acid
You may not qualify if:
- Use of alcohol, cigarettes or illegal drugs
- Pregnancy complications
- Unable or unwilling to breastfeed
- Excessive or insufficient weight gain
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Cepsum
Montreal, Quebec, H3T1J4, Canada
Related Publications (1)
LeMoyne EL, Curnier D, St-Jacques S, Ellemberg D. The effects of exercise during pregnancy on the newborn's brain: study protocol for a randomized controlled trial. Trials. 2012 May 29;13:68. doi: 10.1186/1745-6215-13-68.
PMID: 22643160DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Elise L.LeMoyne
Université de Montréal
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
October 13, 2010
First Posted
October 14, 2010
Last Updated
October 14, 2010
Record last verified: 2010-09