NCT01696201

Brief Summary

Due to physical and physiological changes that occur in pregnant women, depression is very common during this period. Recent research findings indicate that antenatal maternal mood state impacts on babies health. Nowadays, many researchers are focussed on examining the effects of physical exercise on foetal and maternal outcomes. The main aim of this study was to assess the effectiveness of a supervised exercise program consisted of 25-30 minutes of cardiovascular exercise,10 minutes of specific exercises (strength and balance exercises), and 10 minutes of pelvis floor muscles training, on the prevention and treatment of depression in pregnant women. Additionally, the other purpose of the study was to analyze the effects of depression and physical exercise on outcomes. Hypothesis: Pregnant women who do regular exercise during their pregnancies would have a better mood state than pregnant women who are sedentary, without having any negative effect on outcomes.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
160

participants targeted

Target at P50-P75 for not_applicable pregnancy

Timeline
Completed

Started Oct 2009

Longer than P75 for not_applicable pregnancy

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2009

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

September 17, 2012

Completed
11 days until next milestone

First Posted

Study publicly available on registry

September 28, 2012

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2013

Completed
2.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2015

Completed
Last Updated

November 14, 2014

Status Verified

September 1, 2012

Enrollment Period

3.6 years

First QC Date

September 17, 2012

Last Update Submit

November 13, 2014

Conditions

Keywords

Pregnancy, outcomes, depression, mood, physical exercise

Outcome Measures

Primary Outcomes (1)

  • Change from level of depression at the end of the pregnancy

    The Center for Epidemiological Studies-Depression scale (CES-D) was administered to all pregnant women at the beginning and at the end of their pregnancies

    Up to 36 weeks

Secondary Outcomes (2)

  • Maternal outcome

    Time spending in each stages of labor

  • Fetal outcome

    1-5 minutes after labor

Other Outcomes (1)

  • Maternal outcome

    Between 12 and 38 weeks

Study Arms (2)

Control group

NO INTERVENTION

Sedentary pregnant women

Exercise group

EXPERIMENTAL

Exercise program

Behavioral: Exercise group

Interventions

Exercise groupBEHAVIORAL

Supervised physical conditioning program of three 55-60 minute sessions per week during whole pregnancy (from week 9 to 38). Each session consists of 25-30 minutes of cardiovascular exercise,10 minutes of specific exercises (strength and balance exercises), and 10 minutes of pelvic floor muscles training. Aerobic activity was prescribed at light to moderate intensity, aiming for 55-60 of maximal heart rate. All subjects wore a heart rate (HR) monitor (Polar FT7) during the training sessions to ensure that exercise intensity was light to moderate.

Exercise group

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Being healthy and able to exercise following American College of Obstetricians and Gynecologists (ACOG) guidelines
  • Being able to communicate in spanish
  • Giving birth at Hospital Universitario de Fuenlabrada

You may not qualify if:

  • Multiparity
  • Obstetrician complications
  • Being interested in the study after 18 weeks
  • Not being regular in physical exercise program
  • Younger than 18 years old

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidad Politecnica de Madrid

Madrid, Madrid, 28040, Spain

RECRUITING

Related Publications (1)

  • Woodley SJ, Lawrenson P, Boyle R, Cody JD, Morkved S, Kernohan A, Hay-Smith EJC. Pelvic floor muscle training for preventing and treating urinary and faecal incontinence in antenatal and postnatal women. Cochrane Database Syst Rev. 2020 May 6;5(5):CD007471. doi: 10.1002/14651858.CD007471.pub4.

MeSH Terms

Conditions

DepressionMotor Activity

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Officials

  • Ruben Barakat, PhD

    Universidad Politecnica de Madrid

    STUDY DIRECTOR

Central Study Contacts

Maria Perales, PhD student

CONTACT

Ruben Barakat, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD student

Study Record Dates

First Submitted

September 17, 2012

First Posted

September 28, 2012

Study Start

October 1, 2009

Primary Completion

May 1, 2013

Study Completion

June 1, 2015

Last Updated

November 14, 2014

Record last verified: 2012-09

Locations