NCT01009307

Brief Summary

RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at blood and cheek cell samples from patients with glioma.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,709

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2001

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2006

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

November 5, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 6, 2009

Completed
Last Updated

July 22, 2019

Status Verified

July 1, 2019

Enrollment Period

4.8 years

First QC Date

November 5, 2009

Last Update Submit

July 18, 2019

Conditions

Brain and Central Nervous System Tumors

Keywords

adult anaplastic astrocytomaadult diffuse astrocytomaadult pilocytic astrocytomaadult subependymal giant cell astrocytomaadult anaplastic ependymomaadult ependymomaadult myxopapillary ependymomaadult subependymomaadult anaplastic oligodendrogliomaadult oligodendrogliomaadult brain stem gliomaadult giant cell glioblastomaadult glioblastomarecurrent adult brain tumoradult gliosarcomaadult mixed gliomaadult pineal gland astrocytomaadult ependymoblastomaadult medulloblastomaadult supratentorial primitive neuroectodermal tumor (PNET)adult pineoblastomaadult pineocytoma

Outcome Measures

Primary Outcomes (1)

  • Factors related to glioma survival

Interventions

polymorphism analysisGENETIC
laboratory biomarker analysisOTHER
medical chart reviewOTHER

Eligibility Criteria

Age18 Years - 120 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
DISEASE CHARACTERISTICS: * Diagnosis of glioma * Meets 1 of the following criteria: * Participant in the Survival study of San Francisco Bay Area Adult Glioma Study (SFBAAGS) Series 1 and 2 * Treated by UCSF Neuro-Oncology Service; diagnosed between Nov. 1, 2001 and June 30, 2006 and seen between Aug. 1, 2002 and June 30, 2006 * Participant in SFBAAGS Series 3 (not seen at UCSF Neuro-Oncology Service) diagnosed between Nov. 1, 2001 and Oct. 31, 2004 PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

UCSF Helen Diller Family Comprehensive Cancer Center

San Francisco, California, 94115, United States

Location

MeSH Terms

Conditions

Central Nervous System NeoplasmsAstrocytomaEpendymomaGlioma, SubependymalOligodendrogliomaGlioblastomaBrain NeoplasmsGliosarcomaGliomaNeuroectodermal Tumors, PrimitiveMedulloblastomaPinealoma

Interventions

Amplified Fragment Length Polymorphism Analysis

Condition Hierarchy (Ancestors)

Nervous System NeoplasmsNeoplasms by SiteNeoplasmsNervous System DiseasesNeoplasms, NeuroepithelialNeuroectodermal TumorsNeoplasms, Germ Cell and EmbryonalNeoplasms by Histologic TypeNeoplasms, Glandular and EpithelialNeoplasms, Nerve TissueBrain DiseasesCentral Nervous System Diseases

Intervention Hierarchy (Ancestors)

DNA FingerprintingGenetic TechniquesInvestigative TechniquesPolymerase Chain ReactionNucleic Acid Amplification Techniques

Study Officials

  • Margaret Wrensch

    University of California, San Francisco

    STUDY CHAIR

Study Design

Study Type
observational
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 5, 2009

First Posted

November 6, 2009

Study Start

October 1, 2001

Primary Completion

July 1, 2006

Last Updated

July 22, 2019

Record last verified: 2019-07

Locations

US(1)