Study of Blood and Tissue Samples From Patients With Stomach Cancer, Esophageal Cancer, or Gastroesophageal Junction Cancer

NCT00963092 | Unknown

• 3 other identifiers: CRUK-UC-SOCS-03-5-064CDR0000636974EU-20911
• Study Type: observational
• Target: 4,000
• Locations: 1 country
• Sites: 1

Brief Summary

RATIONALE: Collecting and storing samples of tissue, blood, and saliva from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting blood and tissue samples from patients with stomach cancer, esophageal cancer, or gastroesophageal junction cancer, studying them in the laboratory, and storing them for future studies.

Conditions

Adenocarcinoma of the Gastroesophageal Junction; Esophageal Cancer; Gastric Cancer

Keywords

adenocarcinoma of the gastroesophageal junction; recurrent gastric cancer; stage IV gastric cancer; adenocarcinoma of the stomach; adenocarcinoma of the esophagus; recurrent esophageal cancer; stage I esophageal cancer; stage II esophageal cancer; stage III esophageal cancer; stage IV esophageal cancer; stage IA gastric cancer; stage IB gastric cancer; stage IIA gastric cancer; stage IIB gastric cancer; stage IIIA gastric cancer; stage IIIB gastric cancer; stage IIIC gastric cancer

Outcome Measures

Primary Outcomes (1)

• Creation of repository of blood, saliva, and tumor samples

Interventions

DNA analysis GENETIC

RNA analysis GENETIC

microarray analysis GENETIC

protein analysis GENETIC

cytology specimen collection procedure OTHER

laboratory biomarker analysis OTHER

questionnaire administration OTHER

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

DISEASE CHARACTERISTICS: * Must meet 1 of the following criteria: * Diagnosis of gastric or esophageal adenocarcinoma * Diagnosed within the past 5 years * May include gastro-esophageal junction tumor * Spouse or relative of the patient * Samples collected from the European Prospective Investigation of Cancer (EPIC) study * Patients will be approached to participate in the study regardless of their current treatment being curative or palliative, medical or surgical, or if they are currently having follow-up clinical appointments PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * See Disease Characteristics

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• Cancer Research UK: lead

Study Sites (1)

Cancer Research UK at Cambridge Research Institute

Cambridge, England, CB2 0RE, United Kingdom

RECRUITING

MeSH Terms

Conditions

Esophageal Neoplasms; Stomach Neoplasms; Adenocarcinoma Of Esophagus

Interventions

Microarray Analysis

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Head and Neck Neoplasms; Digestive System Diseases; Esophageal Diseases; Gastrointestinal Diseases; Stomach Diseases

Intervention Hierarchy (Ancestors)

Microchip Analytical Procedures; Investigative Techniques

Study Officials

• Carlos Caldas

  Cancer Research UK

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: August 20, 2009
• First Posted: August 21, 2009
• Study Start: August 1, 2002
• Primary Completion: December 1, 2010
• Last Updated: August 12, 2013

Record last verified: 2011-07

Locations

GB (1)