Key Insights

Highlights

Success Rate

80% trial completion

Published Results

25 trials with published results (48%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

17.3%

9 terminated out of 52 trials

Success Rate

79.5%

-7.0% vs benchmark

Late-Stage Pipeline

8%

4 trials in Phase 3/4

Results Transparency

71%

25 of 35 completed with results

Key Signals

25 with results80% success

Data Visualizations

Phase Distribution

47Total
Not Applicable (3)
P 1 (12)
P 2 (28)
P 3 (4)

Trial Status

Completed35
Terminated9
Unknown5
Withdrawn2
Active Not Recruiting1

Trial Success Rate

79.5%

Benchmark: 86.5%

Based on 35 completed trials

Clinical Trials (52)

Showing 20 of 20 trials
NCT04028167Phase 2Active Not Recruiting

Induction FLOT With CROSS CRT for Esophageal Cancer

NCT02013154Phase 1Completed

A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab

NCT04681248Unknown

Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors

NCT01939275Not ApplicableCompletedPrimary

64Cu DOTA-Trastuzumab PET/CT in Studying Patients With Gastric Cancer

NCT02485834Phase 2TerminatedPrimary

FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer

NCT02443324Phase 1Completed

A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer

NCT02918162Phase 2Completed

Perioperative Chemo and Pembrolizumab in Gastric Cancer

NCT02037048Phase 2Unknown

FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma

NCT01307956Phase 2TerminatedPrimary

Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer

NCT03722108Phase 1Terminated

Regorafenib Combined With Irinotecan as Second-line in Patients With Metastatic Gastro-oesophageal Adenocarcinomas

NCT02344810Phase 1Withdrawn

C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer

NCT01333033Phase 2CompletedPrimary

PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy

NCT01212822Phase 2Completed

Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer

NCT04773769Not ApplicableUnknown

Study of Guanábana Leaves for The Treatment of Patients With Gastric, Gastroesophageal Junction, Pancreatic and Colorectal Adenocarcinomas; Hepatocellular Carcinoma, and Low Grade Lymphomas

NCT00064259Phase 1Terminated

A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer

NCT00061932Phase 2CompletedPrimary

Bortezomib With or Without Irinotecan in Treating Patients With Cancer of the Gastroesophageal Junction or Stomach

NCT01183559Phase 1Completed

A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery

NCT01107639Phase 3CompletedPrimary

Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery

NCT01498289Phase 2CompletedPrimary

S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer

NCT01855854Phase 2CompletedPrimary

Second-line Treatment With Icotinib in Esophageal Carcinoma Patients With EGFR Overexpression (IHC 3+) or Positive FISH

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