Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

10.9%

30 terminated/withdrawn out of 275 trials

Success Rate

79.3%

-7.3% vs industry average

Late-Stage Pipeline

14%

39 trials in Phase 3/4

Results Transparency

22%

25 of 115 completed trials have results

Key Signals

40 recruiting25 with results22 terminated8 withdrawn

Enrollment Performance

Analytics

Phase 2
79(35.3%)
Phase 1
73(32.6%)
Phase 3
39(17.4%)
N/A
33(14.7%)
224Total
Phase 2(79)
Phase 1(73)
Phase 3(39)
N/A(33)

Activity Timeline

Global Presence

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Clinical Trials (275)

Showing 20 of 275 trials
NCT05944237Phase 1Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

Role: lead

NCT03741426Phase 2Recruiting

WIRE - Novel Treatments in Renal Cell Cancer

Role: collaborator

NCT07751133Phase 3Recruiting

Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer

Role: collaborator

NCT07776353Recruiting

Understanding New Cachexia Subtypes Through Observational Epidemiological Research

Role: collaborator

NCT03096054Phase 1Completed

A Phase I Trial of LY3143921 Hydrate in Solid Tumours

Role: lead

NCT07440290Phase 2Recruiting

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Role: lead

NCT06632236Phase 1Active Not Recruiting

5G-EMERALD: Amivantamab in Malignant Brain Tumours

Role: collaborator

NCT07172958Phase 1Recruiting

Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

Role: collaborator

NCT05272709Phase 1Recruiting

TT-702 in Patients With Advanced Solid Tumours.

Role: lead

NCT01737242Active Not Recruiting

UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies

Role: collaborator

NCT04307576Phase 3Recruiting

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Role: collaborator

NCT03410030Phase 1Completed

Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM)

Role: collaborator

NCT07721740Not ApplicableNot Yet Recruiting

Using Patient Navigation to Promote Bowel Screening in AAA Attendees.

Role: collaborator

NCT07649525Phase 3Recruiting

Personalising Treatment for Myeloma Patients Based on Initial Response to NHS Treatment and Their Overall Fitness Level

Role: collaborator

NCT05628376Recruiting

TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO

Role: collaborator

NCT05722886Phase 2Recruiting

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Role: lead

NCT02724163Phase 3Active Not Recruiting

International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia

Role: collaborator

NCT05082259Phase 1Active Not Recruiting

ASTEROID: A Trial of ASTX660 in Combination With Pembrolizumab

Role: collaborator

NCT02375204Phase 3Active Not Recruiting

Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

Role: collaborator

NCT05368298Active Not Recruiting

SCOOT: Sample Collection for DART

Role: collaborator