NCT00909792

Brief Summary

The objective of this trial is compare the visual performance, ratings, and preference of two multifocal, soft contact lenses.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
259

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2009

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

May 27, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 28, 2009

Completed
4 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2009

Completed
1.4 years until next milestone

Results Posted

Study results publicly available

October 29, 2010

Completed
Last Updated

June 29, 2012

Status Verified

January 1, 2012

Enrollment Period

1 month

First QC Date

May 27, 2009

Results QC Date

September 16, 2010

Last Update Submit

June 26, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Corrected Distance Binocular Visual Measurement in Normal Illumination Reported as Binocular Distance Visual Acuity

    Tested while reading charts distant to the subject with both eyes together in normal lighting. This outcome is measured in logMAR units (logarithm of the minimum angle of resolution). A logMAR acuity of 0.0 equates to 20/20 Snellen acuity and is considered normal. Positive logMAR values indicate poorer vision and negative values denote better visual acuity.

    After 1 week of wear

Study Arms (2)

Lotrafilcon B / Senofilcon A

OTHER

Lotrafilcon B, followed by Senofilcon A

Device: Lotrafilcon BDevice: Senofilcon A

Senofilcon A / Lotrafilcon B

OTHER

Senofilcon A, followed by Lotrafilcon B

Device: Lotrafilcon BDevice: Senofilcon A

Interventions

Silicone hydrogel, soft, multifocal contact lens

Lotrafilcon B / Senofilcon ASenofilcon A / Lotrafilcon B

Silicone hydrogel, soft, multifocal contact lens

Lotrafilcon B / Senofilcon ASenofilcon A / Lotrafilcon B

Eligibility Criteria

Age35 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be at least 35 years of age
  • Best-corrected distance visual acuity of at least 20/40 in each eye.
  • Spectacle add between +0.75D and +1.50D (inclusive).
  • Able to be fit in available study sphere powers (-1.00 to -5.00D)
  • Currently wearing soft contact lenses at least 5 days a week.

You may not qualify if:

  • Eye injury or surgery within twelve weeks immediately prior to enrollment.
  • Currently enrolled in an ophthalmic clinical trial.
  • Evidence of systemic or ocular abnormality, infection or disease likely to affect successful wear of contact lenses or use of their accessory solutions.
  • Any use of medications for which contact lens wear could be contraindicated as determined by the investigator.
  • Astigmatism ≥ 1.00D.
  • Currently wearing either of the study products.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Presbyopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Priya Janakiraman, OD, FAAO / Head, Global Clinical Affairs
Organization
CIBA VISION

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 27, 2009

First Posted

May 28, 2009

Study Start

May 1, 2009

Primary Completion

June 1, 2009

Study Completion

June 1, 2009

Last Updated

June 29, 2012

Results First Posted

October 29, 2010

Record last verified: 2012-01