NCT00839579

Brief Summary

Exercise training is proved to protect against premature cardiovascular mortality. Additionally there is evidence that relatively high exercise intensity may be an important factor for improving aerobic capacity and endothelial function in patients with post-infarction heart failure, metabolic syndrome, coronary artery disease, as well as in overweight and obese individuals. The aim of this study is to investigate the amount of high-intensity exercise needed to improve aerobic capacity and endothelial function.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable obesity

Timeline
Completed

Started Jan 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2009

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 6, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 9, 2009

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2010

Completed
Last Updated

March 7, 2014

Status Verified

March 1, 2014

Enrollment Period

11 months

First QC Date

February 6, 2009

Last Update Submit

March 6, 2014

Conditions

Obesity

Keywords

slightly overweightmales 35-45 years

Outcome Measures

Primary Outcomes (1)

  • Maximal oxygen consumption and endothelial function

    baseline and 12 weeks followup

Study Arms (2)

4x4min

EXPERIMENTAL

4x4minutes interval group

Other: 1x4 min interval

1x4min

EXPERIMENTAL
Other: 1x4 min interval

Interventions

1x4 min intervalOTHER

Aerobic interval training

1x4min4x4min

Eligibility Criteria

Age35 Years - 45 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • BMI: 25-30
  • Males, 35-45 years
  • Healthy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Norwegian University of Science and Technology

Trondheim, 7489, Norway

Location

Related Publications (1)

  • Tjonna AE, Leinan IM, Bartnes AT, Jenssen BM, Gibala MJ, Winett RA, Wisloff U. Low- and high-volume of intensive endurance training significantly improves maximal oxygen uptake after 10-weeks of training in healthy men. PLoS One. 2013 May 29;8(5):e65382. doi: 10.1371/journal.pone.0065382. Print 2013.

    PMID: 23734250RESULT

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Arnt E Tjønna, PhD

    Norwegian University of Science and Technology

    STUDY CHAIR

  • Ulrik Wisløff, PhD

    Norwegian University of Science and Technology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 6, 2009

First Posted

February 9, 2009

Study Start

January 1, 2009

Primary Completion

December 1, 2009

Study Completion

June 1, 2010

Last Updated

March 7, 2014

Record last verified: 2014-03

Locations

NO(1)