Three Dimensional Morphology of Upper Respiratory Tract and Mandibular Position on Obstructive Sleep Apnea
1 other identifier
observational
20
1 country
1
Brief Summary
Oral appliances, which can maintain patients' jaw forwards during sleep, become more popular in treating obstructive sleep apnea (OSA). However, the exact mechanism of mandible forward on upper airway is not completely known. In this study we will use both static and dynamic MRI to study the 3D morphological changes and dynamic behavior of the upper respiratory tract at different mandible posits. Because in asian society non-obese OSA patients are not uncommonly seen, in this study we focus only on non-obese severe OSA patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Aug 2008
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2008
CompletedFirst Submitted
Initial submission to the registry
September 14, 2008
CompletedFirst Posted
Study publicly available on registry
September 16, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2009
CompletedSeptember 5, 2011
September 1, 2011
1.3 years
September 14, 2008
September 2, 2011
Conditions
Eligibility Criteria
patients referred from sleep center
You may qualify if:
- Severe obstructive sleep apnea (AHI\>=30/hr) age, sex, BMI match control subject
You may not qualify if:
- Patients were excluded when:
- (1) refused to participate in this study,
- (2) had severe obstructive pulmonary disease or active neurological events,
- (3) enrolled in other studies at the same time
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
School of Dentistry, National Taiwan University
Taipei, Taiwan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- hospital
Study Record Dates
First Submitted
September 14, 2008
First Posted
September 16, 2008
Study Start
August 1, 2008
Primary Completion
November 1, 2009
Study Completion
December 1, 2009
Last Updated
September 5, 2011
Record last verified: 2011-09