NCT00664495

Brief Summary

The purpose of the study was to assess the effects of equivalent diet- or exercise-induced weight loss and related insulin resistance in abdominally obese women.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Apr 1999

Longer than P75 for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1999

Completed
4.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2003

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2003

Completed
4.4 years until next milestone

First Submitted

Initial submission to the registry

April 21, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 23, 2008

Completed
Last Updated

April 23, 2008

Status Verified

April 1, 2008

Enrollment Period

4.7 years

First QC Date

April 21, 2008

Last Update Submit

April 22, 2008

Conditions

Obesity

Keywords

Obesity, exercise, diet, insulin resistance

Outcome Measures

Primary Outcomes (2)

  • Abdominal Obesity

    4 months

  • Insulin Resistance

    4 Months

Study Arms (4)

C

NO INTERVENTION

Control

DWL

ACTIVE COMPARATOR

Diet Weight Loss

Behavioral: Diet Weight Loss

EWL

ACTIVE COMPARATOR

Exercise Weight Loss

Behavioral: Exercise Weight Loss

EWS

ACTIVE COMPARATOR

Exercise Without Weight Loss

Behavioral: Exercise Without Weight Loss

Interventions

Diet Weight LossBEHAVIORAL
DWL
Exercise Weight LossBEHAVIORAL
EWL
Exercise Without Weight LossBEHAVIORAL
EWS

Eligibility Criteria

Age20 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Premenopausal women

You may not qualify if:

  • Smokers and diabetics

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Queen's University

Kingston, Ontario, K7L 3N6, Canada

Location

Related Publications (1)

  • Ross R, Janssen I, Dawson J, Kungl AM, Kuk JL, Wong SL, Nguyen-Duy TB, Lee S, Kilpatrick K, Hudson R. Exercise-induced reduction in obesity and insulin resistance in women: a randomized controlled trial. Obes Res. 2004 May;12(5):789-98. doi: 10.1038/oby.2004.95.

    PMID: 15166299RESULT

MeSH Terms

Conditions

ObesityMotor ActivityInsulin Resistance

Interventions

Diet, ReducingExercise

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBehaviorHyperinsulinismGlucose Metabolism DisordersMetabolic Diseases

Intervention Hierarchy (Ancestors)

Diet TherapyNutrition TherapyTherapeuticsDietNutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological PhenomenaMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Robert Ross, PhD

    Queen's University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 21, 2008

First Posted

April 23, 2008

Study Start

April 1, 1999

Primary Completion

December 1, 2003

Study Completion

December 1, 2003

Last Updated

April 23, 2008

Record last verified: 2008-04

Locations

CA(1)