NCT00740766

Brief Summary

The aim of this prospective randomized study is the prevention of excessive weight gain in obese pregnant women. The study will compare perinatal outcomes of obese pregnant women treated in the traditional way to outcomes of nutritionally monitored obese pregnant women and evaluate a preliminary behavioral model applicable to the general practice of obstetrics.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
257

participants targeted

Target at P75+ for not_applicable obesity

Timeline
Completed

Started Jun 1998

Longer than P75 for not_applicable obesity

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 1998

Completed
6.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2005

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2005

Completed
3.3 years until next milestone

First Submitted

Initial submission to the registry

August 22, 2008

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 25, 2008

Completed
Last Updated

June 8, 2009

Status Verified

June 1, 2009

Enrollment Period

6.9 years

First QC Date

August 22, 2008

Last Update Submit

June 4, 2009

Conditions

Keywords

Perinatal OutcomesObesityPregnant women

Outcome Measures

Primary Outcomes (1)

  • Mean weight gain Proportion with excessive weight gain (greater than 15 pounds) Mean postpartum weight increment Newborn birthweight and length, controlled for gestational age Proportion of macrosomia Incidence of co-morbidities

    From entry until 6-weeks postpartum

Study Arms (2)

Monitored

EXPERIMENTAL
Behavioral: Food diary and behavioral model

Unmonitored

NO INTERVENTION

Interventions

The monitored group is to be placed on a prenatal nutritional program consisting of 18 to 24 kcal. per kg. (according to the patient's actual weight) with monitoring each visit. The patients will be weighed each prenatal visit with the monitored patients weighed and blinded to their actual weight (being weighed with her back to the scale). The monitored patients will be requested not to weigh at home and all patients will be asked to wear similar clothing at each visit. All intervention (monitored) group women will be asked to record in a diary all of the foods eaten during each day. These records will be reviewed at each prenatal visit. Six weeks after delivery, the patient will be weighed and will then exit the study. The food diary notebooks will be collected from each patient at the end of the study.

Also known as: Adherence to prenatal nutritional program
Monitored

Eligibility Criteria

Age15 Years - 45 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • BMI greater than 29.9 kg/m2
  • Single fetus

You may not qualify if:

  • Diabetes
  • Hypertension or chronic kidney disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Morristown Memorial Hospital

Morristown, New Jersey, 07962, United States

Location

St. Luke's-Roosevelt Hospital

New York, New York, 10025, United States

Location

Jamaica Hospital Medical Center

New York, New York, 11418, United States

Location

Related Publications (1)

  • Thornton YS, Smarkola C, Kopacz SM, Ishoof SB. Perinatal outcomes in nutritionally monitored obese pregnant women: a randomized clinical trial. J Natl Med Assoc. 2009 Jun;101(6):569-77. doi: 10.1016/s0027-9684(15)30942-1.

MeSH Terms

Conditions

Obesity

Interventions

Diet Records

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

RecordsOrganization and AdministrationHealth Services Administration

Study Officials

  • Yvonne S Thornton, MD, MPH

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 22, 2008

First Posted

August 25, 2008

Study Start

June 1, 1998

Primary Completion

May 1, 2005

Study Completion

May 1, 2005

Last Updated

June 8, 2009

Record last verified: 2009-06

Locations