Effects of Heart Rates and Variability of Heart Rates on Image Quality of Dual-Source CT Coronary Angiography

NCT00632918 | Completed DMC

• 1 other identifier: 96064
• Study Type: observational
• Target: 149
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate the effects of heart rates (including maximum heart rate, average heart rate and minimum heart rate) and variability of heart rate on image quality of DSCT coronary angiography without control of heart rate experienced in our department.

Conditions

CT; Coronary Angiography

Keywords

Image quality; Dual-source CT; Coronary angiography; Heart rate

Outcome Measures

Primary Outcomes (1)

• Compare the effects of the heart rate variables on motion-related image qualities of DSCT coronary angiography between the group 1 patients of chronic beta-blocker users and the group 2 patients without medication of any heart-rate lowering agent.

  About two months

Secondary Outcomes (1)

• Kappa Statistics, Descriptive Statistics, Chi-square test, Independent t-test, Pearson's correlation and linear regression method for statistic analysis.

  About two to three months

Eligibility Criteria

• Age: 21 Years - 78 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The patients or examined persons from Taiwan.

You may not qualify if:

• The patients below 18 year old, patients with status post heterotopic heart transplantation (having two hearts in a chest), patients with status post coronary by-pass surgery and patients with post indwelling of coronary arterial stents

Sponsors & Collaborators

• Far Eastern Memorial Hospital: lead

Study Sites (1)

Department of Medical Imaing, Far Eastern Memorial Hospital

Banqiao District, Taipei, 200, Taiwan

Location

Related Publications (4)

• Leschka S, Scheffel H, Desbiolles L, Plass A, Gaemperli O, Valenta I, Husmann L, Flohr TG, Genoni M, Marincek B, Kaufmann PA, Alkadhi H. Image quality and reconstruction intervals of dual-source CT coronary angiography: recommendations for ECG-pulsing windowing. Invest Radiol. 2007 Aug;42(8):543-9. doi: 10.1097/RLI.0b013e31803b93cf.

  PMID: 17620936 BACKGROUND

• Achenbach S, Ropers D, Kuettner A, Flohr T, Ohnesorge B, Bruder H, Theessen H, Karakaya M, Daniel WG, Bautz W, Kalender WA, Anders K. Contrast-enhanced coronary artery visualization by dual-source computed tomography--initial experience. Eur J Radiol. 2006 Mar;57(3):331-5. doi: 10.1016/j.ejrad.2005.12.017. Epub 2006 Jan 19.

  PMID: 16426789 BACKGROUND

• Johnson TR, Nikolaou K, Wintersperger BJ, Leber AW, von Ziegler F, Rist C, Buhmann S, Knez A, Reiser MF, Becker CR. Dual-source CT cardiac imaging: initial experience. Eur Radiol. 2006 Jul;16(7):1409-15. doi: 10.1007/s00330-006-0298-y. Epub 2006 May 13.

  PMID: 16770652 RESULT

• Matt D, Scheffel H, Leschka S, Flohr TG, Marincek B, Kaufmann PA, Alkadhi H. Dual-source CT coronary angiography: image quality, mean heart rate, and heart rate variability. AJR Am J Roentgenol. 2007 Sep;189(3):567-73. doi: 10.2214/AJR.07.2078.

  PMID: 17715102 RESULT

Biospecimen

Retention: NONE RETAINED

No biospecimens

Study Officials

• Wing-Keung Cheung, MD, CCD

  Far Eastern Memorial Hospital

  PRINCIPAL INVESTIGATOR

• Kao-Lun Wang, MD

  Far Eastern Memorial Hospital

  STUDY CHAIR

• Chen-I Yen, BSc

  Far Eastern Memorial Hospital

  STUDY CHAIR

• Shu-Lin Tsen, BSc

  Far Eastern Memorial Hospital

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: March 3, 2008
• First Posted: March 11, 2008
• Study Start: October 1, 2007
• Study Completion: December 1, 2007
• Last Updated: December 29, 2008

Record last verified: 2008-12

Locations

TW (1)