Optimizing Image Quality in Obese Patients Undergoing Coronary Computed Tomography (CT) Angiography

NCT00468195 | Completed DMC

• 1 other identifier: 2007-002
• Study Type: observational
• Target: 175
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this cardiovascular imaging research is to look at ways to improve the way we can look at the pictures of the heart. Patients undergo CT scans of the heart for a variety of reasons, including symptoms and/or tests suggestive of coronary artery disease (chest pain, shortness of breath, abnormal stress test, follow up exam of known/existing coronary disease, abnormal calcium score, etc.) This study involves finding ways to optimize quality of the scan in persons of size. This is because in patients with a BMI (body mass index) of greater than 40, it is usually difficult to "see" all the arteries around the heart satisfactorily. Body mass index is a number that we can get by putting your height and weight in a formula. The purpose of this study is to use a new computer software program to help us interpret your heart study.

Conditions

Coronary Angiography; Obesity; Coronary Disease

Keywords

tomography; coronary artery disease; obesity

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Volunteers greater than 18 years of age; referred from EC, inpatients, physician offices

You may qualify if:

• Body Mass Index greater than 35
• Age greater than 18 years
• Ability to provide informed consent
• Scheduled to undergo coronary CTA -

You may not qualify if:

• Presence of pre-existing CAD (prior myocardial infarction, prior angiographic evidence of significant coronary artery disease, prior coronary bypass surgery).
• Renal insufficiency (creatinine ≥1.6) or renal failure requiring dialysis.
• Inability or refusal to provide informed consent.
• Pregnancy or unknown pregnancy status.
• Age less than 18 years.
• Patients with known allergy to iodinated contrast.
• \. Computed tomography imaging, or contrast administration, within the past 48 hours.
• Known asthma or reactive airway disease.

Sponsors & Collaborators

• Corewell Health East: lead

Study Sites (1)

William Beaumont Hospital

Royal Oak, Michigan, 48073, United States

Location

MeSH Terms

Conditions

Obesity; Coronary Disease; Coronary Artery Disease

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases

Study Officials

• Kavitha Chinnaiyan, MD

  Corewell Health East

  PRINCIPAL INVESTIGATOR

• Gilbert Raff, MD

  Corewell Health East

  STUDY DIRECTOR

• James Goldstein, MD

  Corewell Health East

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physician

Study Record Dates

• First Submitted: April 30, 2007
• First Posted: May 2, 2007
• Study Start: May 1, 2007
• Study Completion: September 1, 2010
• Last Updated: March 21, 2012

Record last verified: 2012-03

Locations

US (1)