NCT04544384

Brief Summary

All patients in Iceland with STEMI (2008-2018) and NSTEMI (2013-2018) that underwent coronary angiography and had obstructive coronary artery disease were included. Information about patients and angiography results and treatment were obtained from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR). Survival was estimated with Kaplan-Meier method. Cox regression analysis were used to identify significant risk factors for long-term mortality. Relative survival was defined as observed survival divided by expected survival of the population of Iceland

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,257

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2008

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2008

Completed
12.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2020

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

September 2, 2020

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 10, 2020

Completed
Last Updated

September 10, 2020

Status Verified

September 1, 2020

Enrollment Period

12.1 years

First QC Date

September 2, 2020

Last Update Submit

September 9, 2020

Conditions

Acute Myocardial InfarctionCoronary Angiography

Keywords

Acute myocardial infarctionGender differenceLong-term survivalExcess mortality

Outcome Measures

Primary Outcomes (1)

  • Long-term Survival

    Compare treatment and survival of men and women with NSTEMI or STEMI and obstructive coronary artery disease.

    From time of NSTEMI/STEMI to mortality or October 23, 2019

Secondary Outcomes (2)

  • Independent risk factors for mortality

    For NSTEMI (2013-2018) and For STEMI (2008-2018)

  • Relative survival

    For NSTEMI (2013-2018) and For STEMI (2008-2018)

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients, aged 18 years and older, who underwent coronary angiography for acute myocardial infarction (AMI) during the study period. All procedures were performed at Landspitali University Hospital, which is a tertiary referral center and the only institution performing coronary angiographies in Iceland. The study period was from January 1, 2008 to December 31, 2018 for ST elevation myocardial infarction (STEMI and from January 1, 2013 to December 31, 2018 for non-ST elevation myocardial infarction (NSTEMI).

You may qualify if:

  • Patients with NSTEMI during 2013-2018 that underwent coronary angiography
  • Patients with STEMI during 2008-2018 that underwent coronary angiography

You may not qualify if:

  • Normal coronary arteries on coronary angiography
  • Not first presentation of NSTEMI or STEMI during the study period
  • Lost survival data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Ingibjorg Gudmundsdottir, Phd, MD

    Landspitali

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 2, 2020

First Posted

September 10, 2020

Study Start

January 1, 2008

Primary Completion

February 1, 2020

Study Completion

February 1, 2020

Last Updated

September 10, 2020

Record last verified: 2020-09