Assessment of a Teachable Moment for Smoking Cessation

NCT00596440 | Completed Results

• 2 other identifiers: 805712NIH R01CA126969
• Study Type: observational
• Target: 234
• Locations: 1 country
• Sites: 1

Brief Summary

A teachable moment (TM) refers to life events or transitions, such as physician visits, early detection screening feedback, pregnancy, and hospitalization for, and diagnosis of, disease, that inspire health behavior change. Despite strong intuitive appeal of the TM concept and over 150 studies of interventions implemented in a TM, there has been little investigation of the influence of TMs for smoking, particularly for promoting smoking cessation among those indirectly affected by a TM (e.g., relatives of cancer patients). This prospective observational study using a matched-group design will assess whether a lung cancer diagnosis increases enrollment in a smoking cessation program and cessation, and reduces smoking, among the patient's relatives/spouse who smoke. We will compare enrollment in a cessation program and cessation and smoking rates in 2 groups of smokers: 1) relatives/spouses of newly-diagnosed lung cancer patients, and 2) relatives/spouses of patients with an orthopedic condition. We will also explore mediators and moderators of a lung cancer diagnosis as a TM. This study could clarify the TM concept for smoking cessation, shed light on the underlying mechanisms of TMs, and guide future development and implementation of TM-based smoking cessation interventions.

Conditions

Nicotine Dependence

Keywords

smoking; teachable moment; cancer

Outcome Measures

Primary Outcomes (1)

• Accrual Rate (Eligibility Visit)

  Show rate to eligibility visit

  week zero

Secondary Outcomes (2)

• Smoking Cessation Rate

  week nine

• Show Rate at First Treatment Session

  week one

Study Arms (2)

1

Relatives of Cancer Patients

Drug: Transdermal nicotine patch

2

Relatives of Orthopedic Patients

Drug: Transdermal nicotine patch

Interventions

Transdermal nicotine patch DRUG

8 weeks; 4 weeks of 21mg, 2 weeks of 14mg, and 2 weeks of 7mg.

1; 2

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

One group will be relatives/spouses of newly-diagnosed lung or head and neck cancer patients and the second group will be relatives/spouses of orthopedic patients. All participants will be regular smokers (i.e., smoke 10 cigarettes/day on average).

You may qualify if:

• A relative (i.e., sibling, parent, child, grandparent, aunt, uncle, cousin) or spouse of a newly-diagnosed lung or head and neck cancer patient or orthopedic patient (e.g., arthritis, bone and joint infection, foot and ankle conditions, hand, wrist, and elbow conditions such as carpal tunnel syndrome, shoulder and elbow conditions, such as rotator cuff injury, and knee conditions, such as ligament damage repair);
• A regular smoker (i.e., smoke 10 cigarettes/day on average);

You may not qualify if:

• Age 18 or older (to use NRT); and
• Living within \~50 miles of PENN (to allow for meetings at PENN).
• Cannot communicate in English;
• Have current alcohol abuse/dependence;
• Are or have been diagnosed with cancer, asthma, HIV, emphysema, or COPD;
• Have a current medical problem for which NRT is contraindicated such as uncontrolled hypertension (\> 150 over 90), unstable angina, heart attack or stroke within the past 6 months, and liver and/or kidney failure in the last 6-months;
• Currently use monoamine oxidase inhibitors or benzodiazepines, anti-psychotics, and antidepressants, including bupropion;
• Are allergic to adhesive tape or latex, and
• Are a female who is pregnant or nursing.

Sponsors & Collaborators

• University of Pennsylvania: lead
• National Institutes of Health (NIH): collaborator

Study Sites (1)

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

Tobacco Use Disorder; Smoking; Neoplasms

Interventions

Tobacco Use Cessation Devices

Condition Hierarchy (Ancestors)

Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders; Behavior

Intervention Hierarchy (Ancestors)

Therapeutics

Results Point of Contact

• Title: Dr. Robert Schnoll
• Organization: University of Pennsylvania

schnoll@mail.med.upenn.edu

215-746-7143

Study Officials

• Robert A Schnoll, PhD

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: January 8, 2008
• First Posted: January 17, 2008
• Study Start: August 1, 2007
• Primary Completion: December 1, 2011
• Study Completion: February 1, 2012
• Last Updated: August 28, 2015
• Results First Posted: June 11, 2015

Record last verified: 2015-08

Locations

US (1)