Nicotine Dependence
378
31
35
272
Key Insights
Highlights
Success Rate
92% trial completion (above average)
Published Results
152 trials with published results (40%)
Research Maturity
272 completed trials (72% of total)
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 27/100
6.6%
25 terminated out of 378 trials
91.6%
+5.0% vs benchmark
16%
62 trials in Phase 3/4
56%
152 of 272 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 272 completed trials
Clinical Trials (378)
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
Effects of Psilocybin on Craving in Nicotine Dependence
Prevalence and Association of Dysfunctional Breathing With Nicotine Dependence and Physical Activity Among Young Smokers
Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity
Cognitive Task Development and Implementation for Functional MRI Studies
Targeting Orexin to Treat Nicotine Dependence
Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency
Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)
Orexin s Role in the Neurobiology of Substance Use Disorder
Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation
Overcoming Nicotine Dependence to Enable Quitting
Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Individuals
A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users
Optimizing Tobacco Use Treatment for PLWHA
Sex Differences in E-Cigarette Perception
Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Methadone-Maintained Smokers Switching to E-Cigarettes
A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research
Effects of Cannabidiol on Stress and Nicotine Withdrawal