Prize Reinforcement for Smoking Cessation

NCT00865254 | Completed DMC

• 3 other identifiers: RDA021839AR21DA0218391R21DA021839-01
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

Nicotine dependence is prevalent in society, cigarette smoking is associated with several known health risks, and most dependent individuals find it very difficult to stop smoking cigarettes. The present study will test the efficacy of a behavioral smoking cessation treatment, prize-based contingency management, that has not undergone rigorous study with respect to smoking, it but has demonstrated efficacy in reducing use of other substances (e.g. cocaine). If efficacious, prize-based contingency management would add to our repertoire of efficacious smoking cessation treatments.

Conditions

Nicotine Dependence

Keywords

Nicotine Dependence; Smoking; Smoking Cessation; Contingency Management

Outcome Measures

Primary Outcomes (1)

• Expired Carbon Monoxide

  Baseline and treatment phases, 2-mont and 6-month follow up.

Secondary Outcomes (2)

• Self-reported smoking.

  Baseline, throughout treatment, 2-month and 6-month follow up.

• Cotinine levels.

  Baseline, throughout treatment, 2-month and 6-month follow up.

Study Arms (3)

Traditional Contingency Management

EXPERIMENTAL

Standard treatment plus prize based contingency management.

Behavioral: Traditional Contingency Management

Early Enhanced Contingency Management

EXPERIMENTAL

Prize based contingency management with enhanced magnitude early in treatment and reduced magnitude later in treatment.

Behavioral: Early Enhanced Contingency Management

Standard Treatment

ACTIVE COMPARATOR

Counseling and monitoring of smoking cessation.

Behavioral: Standard Treatment

Interventions

Standard Treatment BEHAVIORAL

Brief counseling for smoking cessation followed by continued brief supportive sessions and frequent monitoring of smoking cessation efforts.

Standard Treatment

Traditional Contingency Management BEHAVIORAL

Prize based contingency management condition in which participants have the chance to win incentives (prizes) when they provide biological test results (expired carbon monoxide and cotinine) that are negative for recent smoking. Prize draws result in incentives on an intermittent schedule (50% of draws are prizes). Participants are also provided with brief counseling for smoking cessation followed by continued brief supportive sessions and frequent monitoring of smoking cessation efforts.

Traditional Contingency Management

Early Enhanced Contingency Management BEHAVIORAL

Prize based contingency management condition in which participants have the chance to win incentives (prizes) when they provide biological test results (expired carbon monoxide and cotinine) that are negative for recent smoking. Prize draws result in incentives on an intermittent schedule (100% of draws are prizes in week 1; 33% are prizes in weeks 2-4). Participants are also provided with brief counseling for smoking cessation followed by continued brief supportive sessions and frequent monitoring of smoking cessation efforts.

Early Enhanced Contingency Management

Eligibility Criteria

• Age: 13 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• A current Fagerstrom scale score of 6 or greater;
• Age 13 years old or older (Under age 18, parental consent is required);
• Able to read and understand English.

You may not qualify if:

• Have current severe, uncontrolled psychiatric disorders (i.e., acute suicidality or psychosis);
• Have current substance dependence, other than nicotine or caffeine dependence;
• Are in recovery for pathological gambling; or
• Are already participating in other behavioral or medication smoking cessation programs.

Sponsors & Collaborators

• Wayne State University: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

Wayne State University, Jefferson Avenue Research Clinic

Detroit, Michigan, 48207, United States

Location

Related Publications (1)

• Reid HH, Ledgerwood DM. Depressive symptoms affect changes in nicotine withdrawal and smoking urges throughout smoking cessation treatment: Preliminary results. Addict Res Theory. 2016;24(1):48-53. doi: 10.3109/16066359.2015.1060967. Epub 2015 Jun 26.

  PMID: 27547173 DERIVED

MeSH Terms

Conditions

Tobacco Use Disorder; Smoking; Smoking Cessation

Condition Hierarchy (Ancestors)

Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders; Behavior; Health Behavior

Study Officials

• David M Ledgerwood, Ph.D.

  Wayne State University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: March 17, 2009
• First Posted: March 19, 2009
• Study Start: August 1, 2007
• Primary Completion: July 1, 2011
• Study Completion: July 1, 2011
• Last Updated: June 28, 2013

Record last verified: 2013-06

Locations

US (1)