NCT00400413

Brief Summary

The aim of the research is to investigate phonological processing in deafness and to examine its influence on the neuroanatomy of reading.The basic hypothesis is that insofar as the ability to read is closely related to the ability to segment and represent speech units, the neuroanatomy of reading in deaf would be different from the one of hearing readers.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2003

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2003

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

November 15, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 16, 2006

Completed
4.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

December 22, 2025

Status Verified

December 1, 2025

First QC Date

November 15, 2006

Last Update Submit

December 15, 2025

Conditions

Congenital Deafness

Keywords

NeuropsychologyfMRIReadingPhonologyDeafness

Interventions

fMRIPROCEDURE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adult
  • full education

You may not qualify if:

  • reading impairment
  • fMRI

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clinique Neurologique - Hôpital Civil

Strasbourg, 67091, France

Location

Related Publications (1)

  • Aparicio M, Gounot D, Demont E, Metz-Lutz MN. Phonological processing in relation to reading: an fMRI study in deaf readers. Neuroimage. 2007 Apr 15;35(3):1303-16. doi: 10.1016/j.neuroimage.2006.12.046. Epub 2007 Jan 25.

    PMID: 17329129RESULT

MeSH Terms

Conditions

Deafness

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Marie-Noëlle Metz-Lutz, MD

    Hôpitaux Universitaires de Strasbourg

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 15, 2006

First Posted

November 16, 2006

Study Start

November 1, 2003

Study Completion

August 1, 2011

Last Updated

December 22, 2025

Record last verified: 2025-12

Locations

FR(1)