Deductive Reasoning and Math Learning Difficulty
1 other identifier
interventional
137
1 country
1
Brief Summary
Most studies to date that have examined the factors underlying math achievement in children have focused on basic numerical knowledge. Yet, math skills are clearly not limited to basic numerical knowledge and recent behavioral studies suggest a relationship between math and deductive reasoning skills. The goal of this study is to determine the neural mediators of this relationship using functional magnetic resonance imaging. The investigators will ask children from 8 to 14 to complete a standardized math achievement test, and measure their brain activity while they process deductive arguments. The investigators will then correlate brain activity during reasoning to individual math skills to identify the brain regions in which activity during reasoning is modulated by math skill.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable healthy
Started Apr 2015
Longer than P75 for not_applicable healthy
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 15, 2015
CompletedFirst Submitted
Initial submission to the registry
February 16, 2017
CompletedFirst Posted
Study publicly available on registry
February 23, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 19, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
December 5, 2018
CompletedSeptember 10, 2025
September 1, 2025
3.6 years
February 16, 2017
September 3, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Correlation between brain activity during deductive reasoning and math skill 18 to 24 months later
Brain activity measured using fMRI and math skill measured using a standardized test 18 to 24 months after scanning
18 to 24 months after scanning
Study Arms (1)
Brain activity during reasoning and measure of math skill
EXPERIMENTALBrain activity during reasoning and measure of math skill
Interventions
All participants are scanned while evaluating deductive reasoning problems. Their math skill is also assessed.
Eligibility Criteria
You may qualify if:
- Girl or boy between 8 and 14
- Right-handed
- Affiliated to the French social security
- Whose parents gave informed consent
You may not qualify if:
- Neurological disorders
- Psychiatric disorders
- Birth complications requiring admission into neonatal intensive care unit
- Medication affecting central nervous system processing
- Significant hearing impairment
- Uncorrected visual impairment
- Non-native French speaker
- Contraindications for MRI
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CH le Vinatier
Bron, 69678, France
Related Publications (1)
Schwartz F, Epinat-Duclos J, Leone J, Poisson A, Prado J. Neural representations of transitive relations predict current and future math calculation skills in children. Neuropsychologia. 2020 Apr;141:107410. doi: 10.1016/j.neuropsychologia.2020.107410. Epub 2020 Feb 22.
PMID: 32097661BACKGROUND
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 16, 2017
First Posted
February 23, 2017
Study Start
April 15, 2015
Primary Completion
November 19, 2018
Study Completion
December 5, 2018
Last Updated
September 10, 2025
Record last verified: 2025-09
Data Sharing
- IPD Sharing
- Will not share