Comparison of Central and Peripheral Venous Catheters

NCT00122707 | Completed

• 1 other identifier: LMR1
• Study Type: interventional
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to compare the mechanical and infectious complications of peripheral versus central venous catheters in critically ill patients. Group allocation will be performed by randomization.

Conditions

Respiratory Insufficiency; Shock; Coma

Keywords

catheter-related infection; mechanical complications of catheters

Outcome Measures

Primary Outcomes (3)

• failure to insert line

• mechanical complications of intravenous line insertion

• infectious complications of intravenous lines

Secondary Outcomes (1)

• number of cross-overs (due to impossibility of inserting/maintaining a peripheral line)

Interventions

catheters DEVICE

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients requiring low to moderate doses of continuous catecholamine administration in the ICU
• Patients with 2 failed attempts at inserting a peripheral line
• Patients who require daily change of lines

You may not qualify if:

• Patients aged less than 18 years
• Pregnancy
• Absolute necessity of central venous access (refractory shock/high dose catecholamine infusion)

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Study Sites (1)

Service de Réanimation, Hopital Louis Mourier

Colombes, 92700, France

Location

Related Publications (4)

• Timsit JF. [Updating of the 12th consensus conference of the Societe de Reanimation de langue francaise (SRLF): catheter related infections in the intensive care unit]. Ann Fr Anesth Reanim. 2005 Mar;24(3):315-22. doi: 10.1016/j.annfar.2004.12.022. French.

  PMID: 15792575 BACKGROUND

• Polderman KH, Girbes AJ. Central venous catheter use. Part 1: mechanical complications. Intensive Care Med. 2002 Jan;28(1):1-17. doi: 10.1007/s00134-001-1154-9. Epub 2001 Dec 4.

  PMID: 11818994 BACKGROUND

• Polderman KH, Girbes AR. Central venous catheter use. Part 2: infectious complications. Intensive Care Med. 2002 Jan;28(1):18-28. doi: 10.1007/s00134-001-1156-7. Epub 2001 Nov 29.

  PMID: 11818995 BACKGROUND

• Ricard JD, Salomon L, Boyer A, Thiery G, Meybeck A, Roy C, Pasquet B, Le Miere E, Dreyfuss D. Central or peripheral catheters for initial venous access of ICU patients: a randomized controlled trial. Crit Care Med. 2013 Sep;41(9):2108-15. doi: 10.1097/CCM.0b013e31828a42c5.

  PMID: 23782969 DERIVED

MeSH Terms

Conditions

Respiratory Insufficiency; Shock; Coma; Catheter-Related Infections

Interventions

Catheters

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Unconsciousness; Consciousness Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Infections

Intervention Hierarchy (Ancestors)

Equipment and Supplies

Study Officials

• Jean-Damien Ricard, MD

  Assistance Publique - Hôpitaux de Paris

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: July 19, 2005
• First Posted: July 22, 2005
• Study Start: April 1, 2004
• Study Completion: October 1, 2005
• Last Updated: March 22, 2006

Record last verified: 2005-06

Locations

FR (1)