NCT00959829

Brief Summary

Objectives: (1) To check music and voice message influence on vital signs and facial expressions of patients in physiological or induced comas; (2) To connect the existence of patient's responsiveness with the Glasgow Coma Scale or with the Ramsay Sedation Scale. Method: This was a randomized controlled clinical trial with 30 patients, from two Intensive Care Units, being divided in 2 groups (control and experimental). Their relatives recorded a voice message and chose a song according to the patient's preference. The patients were submitted to 3 sessions for 3 consecutive days.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2004

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2004

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2005

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2005

Completed
4 years until next milestone

First Submitted

Initial submission to the registry

August 13, 2009

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 17, 2009

Completed
Last Updated

June 11, 2010

Status Verified

August 1, 2009

Enrollment Period

1.1 years

First QC Date

August 13, 2009

Last Update Submit

June 10, 2010

Conditions

Keywords

CommunicationComplementary TherapiesIntensive CareEthics

Outcome Measures

Primary Outcomes (1)

  • Vital signs

    3 days; before and after stimulus or silence

Study Arms (1)

silence

PLACEBO COMPARATOR

The control group listened "silence" and was evaluated the same things.

Other: Music and message

Interventions

Experimental group: music and message Control group: silence

Also known as: Patients in state of coma or induced coma
silence

Eligibility Criteria

Age16 Years - 89 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • To be in coma;
  • To be evaluated according to one of the Scales and to have a score in the study range: in physiological comas, score between 3 to 8 Glasgow Coma Scale (GCS); in induced coma, one of the last two scores of Ramsay Sedation Scale (RSS), R5 or R6;
  • To have hearing function preserved according to family;
  • To have written consent from the family or responsible party for the patient's participation in the research.

You may not qualify if:

  • Score between 9 to 15 in GCS or scores R1, R2, R3 or R4 in RSS

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HCFMUSP - Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo

São Paulo, São Paulo, 05403-000, Brazil

Location

Related Publications (1)

  • Puggina AC, Silva MJ. [Vital signs and facial expression of patients in coma]. Rev Bras Enferm. 2009 May-Jun;62(3):435-41. doi: 10.1590/s0034-71672009000300016. Portuguese.

MeSH Terms

Conditions

ComaCommunication

Condition Hierarchy (Ancestors)

UnconsciousnessConsciousness DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 13, 2009

First Posted

August 17, 2009

Study Start

February 1, 2004

Primary Completion

March 1, 2005

Study Completion

September 1, 2005

Last Updated

June 11, 2010

Record last verified: 2009-08

Locations